Results 71 to 80 of about 418,975 (381)

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Determinants of Activity Levels in African Americans With Mild Cognitive Impairment. [PDF]

open access: yes, 2016
Engaging in cognitive, social, and physical activities may prevent cognitive decline. In a sample of older African Americans with mild cognitive impairment (MCI; N=221), we investigated the cross-sectional relationships between activity levels and ...
Casten, PhD, Robin J.   +2 more
core   +2 more sources

Do morbidity measures predict the decline of activities of daily living and instrumental activities of daily living amongst older inpatients? A systematic review

open access: yesInternational journal of clinical practice, 2020
Older adults often suffer from multimorbidity, which results in hospitalisations. These are often associated with poor health outcomes such as functional dependence and mortality.
C. H. Soh   +4 more
semanticscholar   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Effect of Cognitive Training on Daily Function in Older People without Major Neurocognitive Disorder: A Systematic Review

open access: yesGeriatrics, 2019
There is increasing interest in the effect of non-pharmacological treatments on preserving cognition and function in older adults without major neurocognitive disorder (dementia).
Brian J.Y. Fan, Roger Y.M. Wong
doaj   +1 more source

Gendered Expectations Distort Male-Female Differences in Instrumental Activities of Daily Living in Later Adulthood.

open access: yesThe journals of gerontology. Series B, Psychological sciences and social sciences, 2019
OBJECTIVES The ability of older adults to live independently is often assessed with a battery of questions known as Instrumental Activities of Daily Living (IADLs).
C. Sheehan, E. Tucker-Drob
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The Relationship of Basic and Instrumental Activities of Daily Living With the Risk of Developing Pressure Ulcer

open access: yesJournal of Client-centered Nursing Care, 2018
Background: The basic and instrumental activities of daily living are prerequisites for living with a good quality of life. On the contrary, lack of movement and physical inactivity are considered as the main cause of pressure injuries. Accordingly, this
Sahar Mohammadi   +3 more
doaj  

Residential greenness, activities of daily living, and instrumental activities of daily living [PDF]

open access: yesEnvironmental Epidemiology, 2019
Background:We aimed to explore whether higher levels of residential greenness were related to lower odds of disabilities in activities of daily living (ADL) and instrumental activities of daily living (IADL).Methods:We included older adults 65 years of age or older from the Chinese Longitudinal Healthy Longevity Survey.
Zhu, Anna   +5 more
openaire   +4 more sources

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy