Results 161 to 170 of about 4,053,455 (295)

MR-DoC2: Bidirectional Causal Modeling with Instrumental Variables and Data from Relatives. [PDF]

Behav Genet, 2023
Castro-de-Araujo LFS, Singh M, Zhou Y, Vinh P, Verhulst B, Dolan CV, Neale MC.   +6 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Covariate-assisted bounds on causal effects with instrumental variables. [PDF]

J R Stat Soc Series B Stat Methodol
Levis AW, Bonvini M, Zeng Z, Keele L, Kennedy EH.   +4 more
europepmc   +1 more source

The effect of malaria on stunting: an instrumental variables approach. [PDF]

Trans R Soc Trop Med Hyg, 2021
Ateba FF, Doumbia S, Ter Kuile FO, Terlouw DJ, Lefebvre G, Kariuki S, Small DS.   +6 more
europepmc   +1 more source

Assessing the Credibility of Instrumental Variables Inference With Imperfect Instruments Via Sensitivity Analysis [PDF]

instrumental variables,sensitivity ...
Richard A. Ashley.
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Instrumental Variables Analysis and Mendelian Randomization for Causal Inference. [PDF]

J Infect Dis
Moodie EEM, le Cessie S.
europepmc   +1 more source

Are Education and Entrepreneurial Income Endogenous and Do Family Background Variables Make Sense as Instruments?: A Bayesian Analysis [PDF]

Education is a well-known driver of (entrepreneurial) income. The measurement of its influence, however, suffers from endogeneity suspicion. For instance, ability and occupational choice are mentioned as driving both the level of (entrepreneurial) income
Lennart F. Hoogerheide, Jörn H. Block, A. Roy Thurik   +2 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Unraveling the causality between carpal tunnel syndrome and trigger finger through genetic instrumental variables. [PDF]

Eur J Med Res
Huang J, Deng K, Huang S, Lv Z, Zhou S, Chen M.   +5 more
europepmc   +1 more source