Results 81 to 90 of about 513,786 (307)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Technology and Culture: Humans Inventing Themselves [PDF]
, 2013 Since the ancient Greek myth of Prometheus who stole fire from the god, Zeus, humans have been befuddled by their own cleverness. We make useful tools and devices which seem to free humans for higher pursuits only to discover that the unintended ...
Haas, William Paul
core +1 more source
Flexible data input layer architecture (FDILA) for quick-response decision making tools in volatile manufacturing systems [PDF]
, 2008 This paper proposes the foundation for a flexible data input management system as a vital part of a generic solution for quick-response decision making.
Komashie, A, Mousavi, A, Tavakoli, S
core +2 more sources
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Journal of Child Psychology and Psychiatry, 2016 Background Machine learning (ML) provides novel opportunities for human behavior research and clinical translation, yet its application can have noted pitfalls (Bone et al., 2015). In this work, we fastidiously utilize ML to derive autism spectrum disorder (ASD) instrument algorithms in an attempt to improve ...
Bone, Daniel +5 more
openaire +5 more sources
Screen-based musical instruments as semiotic machines [PDF]
, 2006 The ixi software project started in 2000 with the intention to explore new interactive patterns and virtual interfaces in computer music software. The aim of this paper is not to describe these programs, as they have been described elsewhere, but rather ...
Magnusson, Thor
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
14C AMS at SUERC: improving QA data from the 5 MV tandem AMS and 250 kV SSAMS [PDF]
, 2010 In 2003, a National Electrostatics Corporation (NEC) 5MV tandem accelerator mass spectrometer was installed at SUERC, providing the radiocarbon laboratory with 14C measurements to 4–5‰ repeatability.
Anderson, R. +13 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Academic Rheology and Industrial Rheology
Applied Rheology, 1999 This paper is an attempt to highlight the problems faced by industrial rheologists. The problems are far more complex than subjects of usual academic pursuit.
Nakajima Nobuyuki
doaj +1 more source