Results 11 to 20 of about 7,203,866 (304)

Efficacy and safety of ultra-long-acting insulin degludec

Therapeutic Advances in Endocrinology and Metabolism, 2012
All patients with type 1 diabetes and significant numbers of those with type 2 diabetes are treated with insulin. Nonadherence to insulin regimen can impact glycaemic control.
Ammar Wakil, Stephen L. Atkin
doaj   +2 more sources

Di-PEGylated insulin: A long-acting insulin conjugate with superior safety in reducing hypoglycemic events

Acta Pharmaceutica Sinica B
Although the discovery of insulin 100 years ago revolutionized the treatment of diabetes, its therapeutic potential is compromised by its short half-life and narrow therapeutic index.
Zhipeng Zeng, Runcheng Tan, Shi Chen, Haolin Chen, Zhijia Liu, Lixin Liu, Mingqiang Li, Yongming Chen   +7 more
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Insulin glulisine in the management of diabetes

Diabetes, Metabolic Syndrome and Obesity, 2009
Satoru Yamada1,21Diabetes Center, Kitasato Institute Hospital, Tokyo, Japan; 2Department of Internal Medicine, Keio University School of Medicine, Tokyo, JapanAbstract: Insulin glulisine is appealing in principle, but the advantages of this drug over the
Satoru Yamada
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Metabolic implications when employing heavy pre- and post-exercise rapid-acting insulin reductions to prevent hypoglycaemia in Type 1 diabetes patients: a randomised clinical trial [PDF]

, 2014
Aim To examine the metabolic, gluco-regulatory-hormonal and inflammatory cytokine responses to large reductions in rapid-acting insulin dose administered prandially before and after intensive running exercise in male type 1 diabetes patients ...
Dunseath, G, Emma J Stevenson, Richard Bracken, Stevenson Emma J., Michael I. Trenell, Russell, M, Michael I Trenell, Richard M. Bracken, Mark Walker (21700), Campbell Matthew D., Bain, SC, Steven Luzio, Mark Walker, Trenell Michael I., Luzio, S, Trenell, Michael I., Bracken Richard M., Campbell, MD, Bracken, Richard M., Daniel J West, West Daniel J., Emma J. Stevenson (568057), Tuner, D, Steve Luzio, Bracken, Richard, Daniel J. West (568058), Gareth Dunseath (568054), Trenell, MI, Matthew D. Campbell (568052), Dunseath, Gareth, Michael I. Trenell (286474), Trenell, Michael, Mark Russell (206029), Matthew D Campbell, Walker Mark, Tuner Daniel, Steven Luzio (568053), Matthew D. Campbell, Gareth Dunseath, Richard M Bracken, Dunseath Gareth, Walker, Mark, West, Daniel J., Walker, M, Daniel J. West, Bracken, RM, Stevenson, Emma J., Daniel Tuner, Emma J. Stevenson, West, DJ, Russell Mark, Bain, Stephen, Russell, Mark, Stephen C Bain, Bain, Stephen C., Stevenson, Emma, Stephen C. Bain, Campbell, Matthew, Bain Stephen C., Luzio, Steven, Stephen C. Bain (135204), Votruba, Susanne Breuer, Richard M. Bracken (568056), Daniel Tuner (568055), Luzio, Stephen, Mark Russell, Luzio Steven, Tuner, Daniel, Stevenson, EJ, West, Dan   +69 more
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Management and efficacy of intensified insulin therapy starting in outpatients [PDF]

, 1989
Diabetic patients under multiple injection insulin therapy (i.e., intensified insulin therapy, IIT) usually start this treatment during hospitalization. We report here on the logistics, efficacy, and safety of IIT, started in outpatients.
Winkelmann, W., W. Hummerich, M. Steffen, B. Allolio, Allolio, B., G. Ollenschläger, W. Winkelmann, M. Reincke, Hummerich, W., Steffen, M., Ollenschläger, G., Reincke, Martin   +11 more
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Long-acting beta(2)-agonist in addition to tiotropium versus either tiotropium or long-acting beta(2)-agonist alone for chronic obstructive pulmonary disease [PDF]

, 2012
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropium are commonly used for managing persistent symptoms of chronic obstructive pulmonary disease.
Christopher J Cates, Karner, C, Cates, CJ, Charlotta Karner   +3 more
core   +1 more source

Clinical and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes [PDF]

, 2004
Objectives: To assess the clinical and cost-effectiveness of continuous subcutaneous insulin infusion (CSII) compared with multiple daily injections (MDI) in the delivery of intensive insulin therapy for the treatment of diabetes mellitus.
Green, C., N Waugh, Waugh, Norman, M Sidhu, D Hartwell, Colquitt, J. L. (Jill L.), Hartwell, D. (Debbie L.), C Green, J Colquitt, Sidhu, M. K.   +9 more
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Insulin therapy and dietary adjustments to normalize glycemia and prevent nocturnal hypoglycemia after evening exercise in type 1 diabetes: a randomized controlled trial [PDF]

, 2015
Introduction Evening-time exercise is a frequent cause of severe hypoglycemia in type 1 diabetes, fear of which deters participation in regular exercise.
Gonzalez, JT, Walker, Mark, Stevenson, Emma, Gonzalez, Javier T, Campbell, Matthew, Turner, David, Richard Bracken, Bracken, Richard M, Bracken, Richard, Shaw, James, Shaw, JA, West, Daniel J, Walker, M, Bracken, RM, Turner, Daniel, Stevenson, Emma J, Stevenson, EJ, Gonzalez, Javier, Campbell, MD, West, DJ, Turner, D, Shaw, James A, West, Dan   +22 more
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The effect of adding inhaled corticosteroids to tiotropium and long-acting beta(2)-agonists for chronic obstructive pulmonary disease (Review) [PDF]

, 2011
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropiumare commonly used, either on their own or in combination, for managing persistent symptoms of chronic obstructive pulmonary disease ...
Christopher J Cates, Karner, C, Cates, CJ, Charlotta Karner   +3 more
core   +1 more source

The Current Situation Regarding Long-Acting Insulin Analogues Including Biosimilars Among African, Asian, European, and South American Countries; Findings and Implications for the Future

Frontiers in Public Health, 2021
Background: Diabetes mellitus rates continue to rise, which coupled with increasing costs of associated complications has appreciably increased global expenditure in recent years. The risk of complications are enhanced by poor glycaemic control including
Brian Godman, Brian Godman, Brian Godman, Mainul Haque, Trudy Leong, Eleonora Allocati, Santosh Kumar, Salequl Islam, Jaykaran Charan, Farhana Akter, Amanj Kurdi, Amanj Kurdi, Amanj Kurdi, Carlos Vassalo, Muhammed Abu Bakar, Sagir Abdur Rahim, Nusrat Sultana, Farzana Deeba, M. A. Halim Khan, A. B. M. Muksudul Alam, Iffat Jahan, Zubair Mahmood Kamal, Humaira Hasin, Munzur-E-Murshid, Shamsun Nahar, Monami Haque, Siddhartha Dutta, Jha Pallavi Abhayanand, Rimple Jeet Kaur, Godfrey Mutashambara Rwegerera, Godfrey Mutashambara Rwegerera, Renata Cristina Rezende Macedo do Nascimento, Isabella Piassi Dias Godói, Isabella Piassi Dias Godói, Mohammed Irfan, Adefolarin A. Amu, Patrick Matowa, Joseph Acolatse, Robert Incoom, Israel Abebrese Sefah, Israel Abebrese Sefah, Jitendra Acharya, Sylvia Opanga, Lisper Wangeci Njeri, David Kimonge, Hye-Young Kwon, SeungJin Bae, Karen Koh Pek Khuan, Abdullahi Rabiu Abubakar, Ibrahim Haruna Sani, Tanveer Ahmed Khan, Shahzad Hussain, Zikria Saleem, Oliver Ombeva Malande, Oliver Ombeva Malande, Thereza Piloya-Were, Rosana Gambogi, Carla Hernandez Ortiz, Luke Alutuli, Aubrey Chichonyi Kalungia, Iris Hoxha, Vanda Marković-Peković, Biljana Tubic, Biljana Tubic, Guenka Petrova, Konstantin Tachkov, Ott Laius, András Harsanyi, András Inotai, András Inotai, Arianit Jakupi, Svens Henkuzens, Kristina Garuoliene, Jolanta Gulbinovič, Magdalene Wladysiuk, Magdalene Wladysiuk, Jakub Rutkowski, Ileana Mardare, Jurij Fürst, Stuart McTaggart, Sean MacBride-Stewart, Caridad Pontes, Caridad Pontes, Corinne Zara, Eunice Twumwaa Tagoe, Rita Banzi, Janney Wale, Mihajlo Jakovljevic, Mihajlo Jakovljevic   +88 more
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