Results 201 to 210 of about 422,814 (354)

Hypoxia and Leucine Deprivation Induce Human Insulin-Like Growth Factor Binding Protein-1 Hyperphosphorylation and Increase Its Biological Activity

, 2008
Maxim D. Seferovic, Rashad Ali, Hiroyasu Kamei, Suya Liu, Javad Khosravi, Steven H. Nazarian, Victor K. M. Han, Cunming Duan, Madhulika B. Gupta   +8 more
openalex   +1 more source

Insulin‐like Growth Factor (IGF)‐I, IGF‐binding Protein‐3 and Colorectal Adenomas in Japanese Men [PDF]

, 2002
Satoshi Teramukai, Thomas E. Rohan, Kyong‐Yeon Lee, Hiroyuki Eguchi, Oda T, Suminori Kono   +5 more
openalex   +1 more source

Insulin-Like Growth Factor-Binding Protein 6 [PDF]

, 2020
openaire   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Normative data for insulin-like growth factor-1 and insulin-like growth factor binding protein-3 and their determinants in healthy adult males from india: the INDIIGo study. [PDF]

Sci Rep
Shah R, Bansal D, Rastogi P, Sachdev S, Devi N, Sharma RR, Sachdeva N, Agrawal A, Das L, Chanson P, Dutta P.   +10 more
europepmc   +1 more source

Fibronectin Binds Insulin-like Growth Factor-binding Protein 5 and Abolishes Its Ligand-dependent Action on Cell Migration

, 2004
Qijin Xu, Ben Yan, Shenghua Li, Cunming Duan   +3 more
openalex   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

Plasma Insulin-like Growth Factor-Binding Protein-7 Is Positively Associated with Age, Obesity, Mortality, and Cancer in Postmenopausal Women. [PDF]

Cancer Epidemiol Biomarkers Prev
Orenduff MC, Pieper CF, Allott EH, Coleman MF, Jung SY, Vitolins MZ, Fenton JI, Chen C, Kroenke CH, Tabung FK, Barac A, Paskett ED, Pollak MN, Hays-Grudo J, Chang S, Hursting SD.   +15 more
europepmc   +1 more source

The diagnostic value of serum insulin-like growth factor binding protein 7 in gastric cancer. [PDF]

PeerJ, 2023
Liu CT, Wu FC, Zhuang YX, Huang XY, Li XH, Qu QQ, Peng YH, Xu YW, Chen SL, Huang XC.   +9 more
europepmc   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source