Results 191 to 200 of about 200,349 (246)

Characteristics of Protein Profiling and Biomarkers in Aortic Regurgitation With Heart Failure. [PDF]

J Am Heart Assoc
Ni CY, Hou HT, Zhao HG, Ni YM, Ma L, He GW.   +5 more
europepmc   +1 more source

H19 lncRNA in programming prenatal development and DOHaD due to maternal obesity. [PDF]

Life Sci
Islam S, Du M.
europepmc   +1 more source

Clinical spectrum of extreme insulin resistance syndromes treated with rhIGF-1: A single-center experience.

J Clin Endocrinol Metab
Improda N, Katugampola H, Cerbone M, Shah P, Alexander S, Atterbury A, Hadj-Rabia S, Peters CJ, Semple RK, Dattani MT.   +9 more
europepmc   +1 more source

Cellular Actions of the Insulin-Like Growth Factor Binding Proteins [PDF]

Endocrine Reviews, 2002
In addition to their roles in IGF transport, the six IGF-binding proteins (IGFBPs) regulate cell activity in various ways. By sequestering IGFs away from the type I IGF receptor, they may inhibit mitogenesis, differentiation, survival, and other IGF-stimulated events.
Robert Baxter, Sue M Firth, Firth Sue M
exaly   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Phosphorylation of insulin-like growth factor binding proteins

Molecular and Cellular Endocrinology, 1997
Insulin-like growth factor (IGF) binding proteins (IGFBPs) play a key role in regulating the availability of IGFs in the circulation and the extracellular environment. Three of these proteins-IGFBP-1, IGFBP-3 and IGFBP-5-are known to be serine-phosphorylated in their central domains, and the others have possible target sites for serine/threonine ...
J A, Coverley, R C, Baxter
openaire   +2 more sources

The Role of Insulin-Like Growth Factor Binding Proteins

Neuroendocrinology, 2006
Insulin-like growth factors (IGFs) are fundamental cell regulators with an evolutionary conserved role synchronising tissue growth, development and function according to metabolic conditions. Although structurally very similar to insulin, the IGFs act in a very different way as cell regulators. Whereas insulin is stored in a specific gland and released
Perks, Claire, Holly, Jeffrey M P
openaire   +3 more sources

Insulin-like growth factor binding protein proteolysis

Trends in Endocrinology & Metabolism, 2003
High-affinity interactions between insulin-like growth factors (IGF-I and IGF-II) and insulin-like growth factor-binding proteins (IGFBP-1, -2, -3, -4, -5 and -6) antagonize the binding of IGF to the type 1 IGF receptor. Proteases found in a variety of biological fluids can degrade IGFBP 1-6 into fragments that have a greatly reduced affinity for IGF-I
R Clay, Bunn, John L, Fowlkes
openaire   +2 more sources

Insulin‐like growth factor‐binding protein 1 and insulin‐like growth factor‐binding protein 3 in pre‐eclampsia

BJOG: An International Journal of Obstetrics & Gynaecology, 1996
Objective To investigate circulating levels of insulin‐like growth factor‐binding protein 1 (IGFBP‐1) and IGFBP‐3 in the mother and the fetus in pregnancies complicated by pre‐eclampsia, and the relationship between serum levels of IGFBPs and fetal birthweight.Design A prospective study over an 18 month period.Setting A tertiary care ...
H S, Wang, J D, Lee, B J, Cheng, Y K, Soong   +3 more
openaire   +2 more sources

Insulin‐like growth factor binding proteins: a proposed superfamily

Acta Paediatrica, 1999
Hwa V, Oh Y, Rosenfeld RG. Insulin‐like growth factor binding proteins: a proposed superfamily. Acta Pzdiatr 1999; Suppl 428:37‐45. Stockholm. ISSN 0803‐5326The conventional concept is that the insulin‐like growth factor binding proteins (IGFBPs) are cysteine‐rich proteins, with conserved N‐ and C‐domains, that are capable of binding insulin‐like ...
V, Hwa, Y, Oh, R G, Rosenfeld
openaire   +4 more sources