Results 11 to 20 of about 239,986 (298)

Adult growth hormone deficiency treatment with a combination of growth hormone and insulin-like growth factor-1 resulting in elevated sustainable insulin-like growth factor-1 and insulin-like growth factor binding protein 3 plasma levels: a case report [PDF]

Journal of Medical Case Reports, 2010
Introduction Adult Growth hormone Deficiency is a well known phenomenon effecting both males and females. Adult Growth Hormone Deficiency is marked by a number of neuropsychiatric, cognitive performance, cardiac, metabolic, muscular, and bone symptoms ...
Madigan Margaret, Chen Thomas JH, Yeldandi Swetha, Damle Uma J, Bowirrat Abdalla, Braverman Eric R, Kerner Mallory, Huang Stanley X, Savarimuthu Stella, Blum Kenneth   +9 more
doaj   +2 more sources

Insulin-like growth factor binding protein-3 is required for the regulation of rat oval cell proliferation and differentiation in the 2AAF/PHX model

Hepatic Medicine: Evidence and Research, 2010
Nicole C Steiger-Luther1, Houda Darwiche1, Seh-Hoon Oh1, Jennifer M Williams1, Bryon E Petersen1,21Department of Pathology, Immunology and Laboratory Medicine, 2Program in Stem Cell Biology and Regenerative Medicine, College of Medicine, University of ...
Nicole C Steiger-Luther, Houda Darwiche, Seh-Hoon Oh, et al   +3 more
doaj   +1 more source

Transferrin binds insulin‐like growth factors and affects binding properties of insulin‐like growth factor binding protein‐3 [PDF]

FEBS Letters, 2001
In the circulation, most of the insulin‐like growth factors (IGFs) are bound to a ternary 150 kDa complex with IGF‐binding protein (IGFBP)‐3 and the acid labile subunit. In the current study, we identify transferrin (Tf) by mass spectrometry, and immunoprecipitation as a component of a major IGF‐binding fraction separated from human plasma.
Storch, S., Kubler, B., Honing, S., Ackmann, M., Zapf, J., Blum, W., Braulke, Thomas   +6 more
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Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3 in Alzheimer's Disease [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2012
Few large studies have been conducted to assess the relationship between circulating IGF and late-life cognition.The aim of the study was to assess the relationship between IGF-I and IGF binding protein-3 (IGFBP-3) serum levels and cognitive impairment, including Alzheimer's disease (AD).In this multicentric cross-sectional study, 694 elderly subjects (
Duron, Emmanuelle, Funalot, Benoît, Brunel, Nadège, Coste, Joël, Quinquis, Laurent, Viollet, Cécile, Belmin, Joël, Jouanny, Pierre, Pasquier, Florence, Tréluyer, Jean-Marc, Epelbaum, Jacques, Le Bouc, Yves, Hanon, Olivier   +12 more
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Insulin-like Growth Factor-binding Protein-3 Binds Fibrinogen and Fibrin [PDF]

Journal of Biological Chemistry, 1999
Following tissue injury, a fibrin network formed at the wound site serves as a scaffold supporting the early migration of stromal cells needed for wound healing. Growth factors such as insulin-like growth factor-I (IGF-I) concentrate in wounds to stimulate stromal cell function and proliferation.
P G, Campbell, S K, Durham, J D, Hayes, A, Suwanichkul, D R, Powell   +4 more
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The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance

Technology in Cancer Research & Treatment, 2020
RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients ...
Jing Zhang MS, Fanghui Ding MD, Dan Jiao MS, Qiaozhi Li MS, Hong Ma MS   +4 more
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Insulin-like growth factor (IGF)-I and IGF binding proteins axis in diabetes mellitus [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2015
Increasing evidence suggests an important role of the insulin-like growth factor (IGF)-IGF binding protein (IGFBP) axis in the maintenance of normal glucose and lipid metabolism. Significant changes occur in the local IGF-I-IGFBPs environment in response
Min Sun Kim, Dae-Yeol Lee
doaj   +1 more source

Serum insulin like growth factor-1 (IGF-1) and insulin like growth factor binding protein-3 (IGFBP-3) levels in liver cirrhosis

The Turkish Journal of Gastroenterology, 2007
Background/aims: Impaired growth hormone-insulin like growth factor system in hepatic cirrhosis leads to cirrhosis-relaled complications. In this study, we aimed to investigate whether serum levels of insulin like growth factor-1 and insulin like growth ...
Önder ÇOLAKOĞLU, Bengür TAŞKIRAN, Gül ÇOLAKOĞLU, Servet KIZILDAĞ, Fulya ÖZCAN ARI, Belkıs ÜNSAL   +5 more
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Cardiovascular disease risk markers in children under 10 years of age and their relationship with serum concentrations of IGF-1, IGFBP-1, IGFBP-2 and IGFBP-3

Revista de la Facultad de Medicina, 2020
Introduction: Any type of nutritional imbalance experienced during childhood will affect the health of an individual, both in their childhood and their adulthood.
Sorany Vera, Tatiana Figueroa, Luz Helena Aranzalez, Ismena Mockus   +3 more
doaj   +1 more source

Factors regulating insulin-like growth factor-binding protein-3 binding, processing, and potentiation of insulin-like growth factor action [PDF]

Endocrinology, 1996
In this study, we investigated the effects of various biochemical and pharmacological agents on insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) cell binding and action in cultured bovine fibroblasts. When cells were preincubated for 48 h with 50 nM recombinant human (rh) IGFBP-3, IGF-I-stimulated [3H]aminoisobutyric acid ([125H]AIB) uptake
C A, Conover, J T, Clarkson, L K, Bale
openaire   +4 more sources