Results 181 to 190 of about 361,919 (237)

Seric Molecular Markers Correlated with Stroke Rehabilitation Outcomes: A Narrative Review. [PDF]

open access: yesLife (Basel)
Ene BG   +6 more
europepmc   +1 more source

Insulin-like growth factor binding protein proteolysis

Trends in Endocrinology & Metabolism, 2003
High-affinity interactions between insulin-like growth factors (IGF-I and IGF-II) and insulin-like growth factor-binding proteins (IGFBP-1, -2, -3, -4, -5 and -6) antagonize the binding of IGF to the type 1 IGF receptor. Proteases found in a variety of biological fluids can degrade IGFBP 1-6 into fragments that have a greatly reduced affinity for IGF-I
R Clay, Bunn, John L, Fowlkes
openaire   +2 more sources

Insulin-like growth factors and their binding proteins

Physiological Reviews, 1990
Article de synthese sur les facteurs de croissance IGF et leurs proteines de liaisons: structure, biosynthese, regulation de la production paracrine et endocrine, recepteurs et transmission du signal intracellulaire, activite biologique in vitro et in vivo chez les ...
V R, Sara, K, Hall
openaire   +4 more sources

Colocalization of insulin-like growth factor-binding protein with insulin-like growth factor I

American Journal of Physiology-Renal Physiology, 1991
We report the localization of insulin-like growth factor I (IGF-I) and a 25-kDa form of insulin-like growth factor-binding protein (IGF-BP-1) in adult rat kidney. The antigens were localized using a rabbit anti-human IGF-I antibody, and a rabbit anti-human IGF-BP-1 antibody raised against human 25-kDa IGF-BP-1 purified from amniotic fluid ...
S, Kobayashi   +2 more
openaire   +2 more sources

Phosphorylation of insulin-like growth factor binding proteins

Molecular and Cellular Endocrinology, 1997
Insulin-like growth factor (IGF) binding proteins (IGFBPs) play a key role in regulating the availability of IGFs in the circulation and the extracellular environment. Three of these proteins-IGFBP-1, IGFBP-3 and IGFBP-5-are known to be serine-phosphorylated in their central domains, and the others have possible target sites for serine/threonine ...
J A, Coverley, R C, Baxter
openaire   +2 more sources

Insulin-Like Growth Factors, Insulin-Like Growth Factor Binding Proteins and Ovarian Androgen Production

Hormone Research, 1994
Increasing evidence indicates that the ovary contains an insulin-like growth factor (IGF) system complete with ligands, binding proteins, and receptors. Through their interaction with IGF receptors on theca-interstitial cell surface membranes, the ligands, IGF-I and IGF-II, synergize with luteinizing hormone (LH) to increase ovarian androgen production.
openaire   +2 more sources

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