Results 201 to 210 of about 361,919 (237)

Insulin-like growth factor binding proteins as glucoregulators

Metabolism, 1995
Circulating insulin-like growth factors (IGFs) represent an important pool of potential hypoglycemic activity, which is largely inhibited by their sequestration in a heterotrimeric complex comprising growth factor, IGF-binding protein-3 (IGFBP-3), and acid-labile subunit (ALS). Less than 1% of total IGFs circulate in the free form, yet even this amount
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Insulin‐Like Growth Factor Binding Proteins

Comprehensive Physiology, 1990
Abstract The sections in this article are: Gene Structures Insulin‐Like Growth Factor Binding Protein 1 Insulin‐Like Growth Factor Binding Protein 2
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Insulin-like growth factor-I and insulin-like growth factor-binding proteins in the nephrotic syndrome

Pediatric Nephrology, 1996
Similar to findings in the nephrotic syndrome in humans, rats with the doxorubicin-induced nephrotic syndrome (which resembles minimal change disease) have reduced serum levels of insulin-like growth factor-I (IGF-I). This is mainly caused by glomerular ultrafiltration of IGF-I-containing binding protein complexes, primarily of a molecular weight of ...
S M, Feld, R, Hirschberg
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Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3

Journal of the American Academy of Dermatology, 2000
A recent report suggested that men with vertex balding have higher levels of plasma insulin-like growth factor 1 (IGF-1). The association of its major carrier protein, insulin-like growth factor binding protein 3 (IGFBP-3), with male pattern hair loss has not been examined.We evaluated the relations of plasma concentrations of IGF-1 and IGFBP-3 with ...
E A, Platz, M N, Pollak, W C, Willett, E, Giovannucci   +3 more
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Insulin-like growth factor 2 and insulin-like growth factor binding protein 2 expression in hepatoblastoma

Human Pathology, 1995
The expression of insulin-like growth factor 2 (IGF2) and insulin-like growth factor binding protein 2 (IGFBP2) in 11 cases of hepatoblastoma was studied by means of in situ mRNA hybridization using digoxigenin (DIG)-labeled riboprobes. The results showed that both IGF2 and IGFBP2 transcripts are present in hepatoblastoma and that their expression is ...
S N, Akmal, K, Yun, J, MacLay, Y, Higami, T, Ikeda   +4 more
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Insulin‐like growth factor binding proteins: a proposed superfamily

Acta Paediatrica, 1999
Hwa V, Oh Y, Rosenfeld RG. Insulin‐like growth factor binding proteins: a proposed superfamily. Acta Pzdiatr 1999; Suppl 428:37‐45. Stockholm. ISSN 0803‐5326The conventional concept is that the insulin‐like growth factor binding proteins (IGFBPs) are cysteine‐rich proteins, with conserved N‐ and C‐domains, that are capable of binding insulin‐like ...
V, Hwa, Y, Oh, R G, Rosenfeld
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Testosterone increases insulin-like growth factor-1 and insulin-like growth factor-binding protein.

Annals of clinical and laboratory science, 1995
Growth of the male external genitalia is primarily regulated by androgens; however, several observations suggest growth hormone (GH) or a GH dependent factor, such as insulin-like growth factor-1 (IGF-1), might also be involved. It is hypothesized that testosterone (T) might induce the synthesis of IGF-1 or IGF-binding protein (IGF-BP) which could ...
W S, Ashton, B M, Degnan, A, Daniel, G L, Francis   +3 more
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Insulin-Like Growth Factor Binding Protein-3

1994
In plasma and other biological fluids insulinlike growth factors are bound to a family of structurally homologous binding proteins (IGFBPs).
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Insulin-Like Growth Factor Binding Protein-6: The “Forgotten” Binding Protein?

Hormone and Metabolic Research, 1999
Insulin-like growth factor binding protein-6 (IGFBP-6) differs from IGFBPs 1-5 in that it binds IGF-II with marked preferential affinity over IGF-I. Human and rat IGFBP-6 lack 2 and 4 N-terminal cysteines and therefore the Gly-Cys-Gly-Cys-Cys motif present in IGFBPs 1-5.
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Insulin-Like Growth Factor Binding Protein-1

1994
IGFBP-I is a 25.3 kDa protein and is one of 6 structurally related proteins which bind and modulate the bioactivity of IGF-I and IGF-II. It is synthesized primarily in the liver and decidualized uterine endometrium, and is distributed primarily in the intravascular space and lymph.
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