Results 191 to 200 of about 530,055 (311)

The Effects of Insulin-Like Growth Factor I and BTP-2 on Acute Lung Injury. [PDF]

Int J Mol Sci, 2021
Munoz K, Wasnik S, Abdipour A, Bi H, Wilson SM, Tang X, Ghahramanpouri M, Baylink DJ.   +7 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Growth hormone/insulin-like growth factor I axis in health and disease states: an update on the role of intra-portal insulin. [PDF]

Front Endocrinol (Lausanne)
Yuen KCJ, Hjortebjerg R, Ganeshalingam AA, Clemmons DR, Frystyk J.   +4 more
europepmc   +1 more source

Essential Amino Acid Intake Is Required for Sustaining Serum Insulin-like Growth Factor-I Levels but Is Not Necessarily Needed for Body Growth. [PDF]

Cells, 2022
Nishi H, Uchida K, Saito M, Yamanaka D, Nagata H, Tomoshige H, Miyata I, Ito K, Toyoshima Y, Takahashi SI, Hakuno F, Takenaka A.   +11 more
europepmc   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Associations between Bronchopulmonary Dysplasia, Insulin-like Growth Factor I and Nutrition. [PDF]

Nutrients
Yumani DFJ, Walschot FH, Lafeber HN, van Weissenbruch MM.   +3 more
europepmc   +1 more source

Reduced Insulin-Like Growth Factor-I Effects in the Basal Forebrain of Aging Mouse. [PDF]

Front Aging Neurosci, 2021
Zegarra-Valdivia JA, Chaves-Coira I, Fernandez de Sevilla ME, Martinez-Rachadell L, Esparza J, Torres-Aleman I, Nuñez A.   +6 more
europepmc   +1 more source

Maternal serum insulin-like growth factor-I

Journal of the Chinese Medical Association, 2014
openaire   +2 more sources

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

RETRACTED: Sarfstein et al. Identification of Insulin-Like Growth Factor-I Receptor (IGF-IR) Gene Promoter-Binding Proteins in Estrogen Receptor (ER)-Positive and ER-Depleted Breast Cancer Cells. <i>Cancers</i> 2010, <i>2</i>, 233-261. [PDF]

Cancers (Basel)
Sarfstein R, Belfiore A, Werner H.
europepmc   +1 more source