Results 181 to 190 of about 31,941,529 (292)

Upregulation of Insulin-like Growth Factor-I in Response to Chemotherapy in Children with Acute Lymphoblastic Leukemia. [PDF]

Int J Mol Sci
Kocadag HB, Weischendorff S, De Pietri S, Nielsen CH, Rathe M, Als-Nielsen B, Hasle H, Juul A, Müller K, Sørum ME.   +9 more
europepmc   +1 more source

Insulin and insulin-like growth factor-I receptors in astrocytes exert different effects on behavior and Alzheimer´s-like pathology. [PDF]

F1000Res, 2022
Zegarra-Valdivia J, Fernandez AM, Martinez-Rachadell L, Herrero-Labrador R, Fernandes J, Torres Aleman I.   +5 more
europepmc   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Associations between Bronchopulmonary Dysplasia, Insulin-like Growth Factor I and Nutrition. [PDF]

Nutrients
Yumani DFJ, Walschot FH, Lafeber HN, van Weissenbruch MM.   +3 more
europepmc   +1 more source

The Effects of Insulin-Like Growth Factor I and BTP-2 on Acute Lung Injury. [PDF]

Int J Mol Sci, 2021
Munoz K, Wasnik S, Abdipour A, Bi H, Wilson SM, Tang X, Ghahramanpouri M, Baylink DJ.   +7 more
europepmc   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Correction: Nishikawa et al. Insulin-like Growth Factor-I Reduces Collagen Production by Hepatic Stellate Cells Through Stimulation of Collagen Degradation System via mTOR-Dependent Signaling Pathway. <i>Biomedicines</i> 2025, <i>13</i>, 566. [PDF]

Biomedicines
Nishikawa T, Ohtomo N, Inoue Y, Takahashi M, Ikeda H, Koike K, Yamamichi N, Fujishiro M, Tomiya T.   +8 more
europepmc   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Growth hormone/insulin-like growth factor I axis in health and disease states: an update on the role of intra-portal insulin. [PDF]

Front Endocrinol (Lausanne)
Yuen KCJ, Hjortebjerg R, Ganeshalingam AA, Clemmons DR, Frystyk J.   +4 more
europepmc   +1 more source

Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons. [PDF]

Mol Psychiatry, 2022
Fernández de Sevilla ME, Pignatelli J, Zegarra-Valdivia JA, Mendez P, Nuñez A, Torres Alemán I.   +5 more
europepmc   +1 more source