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The Insulin-Urothelial Axis: Evaluating Insulin Resistance as a Convergent Driver of Bladder Cancer Across Diverse Risk Factor Profiles. [PDF]
Tarantino G +3 more
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Angiogenesis and inflammation in the retinopathy risk of insulin and semaglutide - a review. [PDF]
Lu M.
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Synthetic insulin-like growth factor II
Biochemical and Biophysical Research Communications, 1985Human insulin-like growth factor II with 67 amino acid residues and three disulfide bridges has been synthesized by the solid-phase method. Homogeneity of the synthetic product is ascertained by chromatofocusing, high performance liquid chromatography and amino acid analysis.
C H, Li +3 more
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Insulin‐Like Growth Factor II Effects Mediated through Insulin‐Like Growth Factor II Receptors
Acta Paediatrica, 1990ABSTRACT. Insulin‐like growth factor II (IGF‐II) resembles the homologous peptide insulin‐like growth factor I (IGF‐I) in that it stimulates cellular growth in vitro. This effect is generally believed to be mediated through IGF type 1 receptors; the role of the IGF type 2 receptor remains, as yet, unknown.
M, Tally, K, Hall
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Immunoreactive insulin-like growth factor II in urine
Acta Endocrinologica, 1990Abstract. Insulin-like growth factor II and insulin-like growth factor binding protein-1 were identified and quantified in the urine of 23 healthy subjects between 17 and 76 years of age. IGF-II was measured after separation by gel chromatography at low pH and compared with IGF-I levels in the same samples, whereas IGF binding protein-1 was measured in
W, Zumkeller, K, Hall
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Secretion of insulin-like growth factor II into milk
Biochemical and Biophysical Research Communications, 1992125I-labeled insulin-like growth factor II (IGF-II) was infused directly into the pudic artery supplying one gland of lactating goats (n = 4). Maximum specific activity for [125I]IGF-II transferred into milk from the infused gland was reached 60 min after that in plasma and was 2.5 fold greater than in milk from the non-infused gland.
C G, Prosser, I R, Fleet
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Chemical synthesis of insulin‐like growth factor II
International Journal of Peptide and Protein Research, 1985Human insulin‐like growth factor II (IGF‐II) with 67 amino acids and three disulfide bridges has been synthesized by the solid‐phase method. The synthetic hormone is shown to be homogeneous in high performance liquid chromatography (HPLC), high performance partition chromatography (HPPC), and chromatofocusing.
D, Yamashiro, C H, Li
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Insulin-Like Growth Factor II in Hepatocellular Carcinoma
Biomarkers in Medicine, 2007Hepatocellular carcinoma is one of the most common malignant human tumors. Hepatocarcinogenesis is a multistep process with a multifactorial etiology. Chronic hepatitis B and hepatitis C virus infection, alcohol drinking and cirrhosis of any etiology are the major risk factors for hepatocellular carcinoma.
Jeng-Eing, Jeng +4 more
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Biochemical and Biophysical Research Communications, 1986
Specific high affinity membrane receptor(s) for insulin-like growth factor II have been characterized in two cell lines which produce this hormone and have the ability to proliferate in serum-free media. These receptor(s) have no affinity for either insulin or biosynthetic insulin-like growth factor I.
P D, Lee +4 more
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Specific high affinity membrane receptor(s) for insulin-like growth factor II have been characterized in two cell lines which produce this hormone and have the ability to proliferate in serum-free media. These receptor(s) have no affinity for either insulin or biosynthetic insulin-like growth factor I.
P D, Lee +4 more
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The International Journal of Biochemistry & Cell Biology, 1999
The insulin-like growth factor II receptor mediates endocytosis of insulin-like growth factor II, resulting in growth factor degradation in lysosomes. This degradation is an important regulator of growth factor activity in vivo, as shown by the phenotype of receptor deficient mice.
C M, Nolan, M A, Lawlor
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The insulin-like growth factor II receptor mediates endocytosis of insulin-like growth factor II, resulting in growth factor degradation in lysosomes. This degradation is an important regulator of growth factor activity in vivo, as shown by the phenotype of receptor deficient mice.
C M, Nolan, M A, Lawlor
openaire +2 more sources

