Results 211 to 220 of about 198,823 (254)

Insulin-Like Growth Factor-II: Possible Local Growth Factor in Pheochromocytoma*

The Journal of Clinical Endocrinology & Metabolism, 1990
Pheochromocytomas, neural crest tumors, express an abundance of insulin-like growth factor-II (IGF-II). To assess further the potential for IGF-II to play an autocrine role for these tumors, we measured 1) IGF-II content by RRA in 7 pheochromocytomas and peripheral blood in these patients, 2) IGF-II receptors by Western analysis, and 3) characterized ...
M C, Gelato, J, Vassalotti
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Insulin-like growth factor II and nonsuppressible insulin-like activity levels in newborns

American Journal of Obstetrics and Gynecology, 1990
We measured insulin-like growth factor II and nonsuppressible insulin-like activity levels in the sera of newborn infants with different birth weights and gestational ages to determine the significance of these peptides in fetal growth. Our results obtained by use of one-way analysis of variance showed that the insulin-like growth factor II and ...
N A, Samaan, P N, Schultz, F K, Pham
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Spatial and temporal expression of insulin-like growth factor-I, insulin-like growth factor-II and the insulin-like growth factor-I receptor in the sheep fetal mammary gland

Journal of Dairy Research, 1999
The mammary gland is an example of a tissue of epidermal origin that depends for the development of its characteristic morphology on underlying mesenchymal cells. The interaction between mesenchyme and epithelium appears to be mediated by polypetide growth factors.
Forsyth, Isabel A., Gabai, Gianfranco, Morgan, Geoff   +2 more
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Insulin-like Growth Factor-II as a Paracrine Growth Factor in Human Neuroblastoma Cells

Experimental Cell Research, 1995
The human neuroblastoma line, SK-N-SH, has been subcloned into SH-SY5Y, a neuroblast N cell line, and SH-EP, an epithelial Schwann S cell line. We have previously shown that SH-SY5Y neuroblastoma cells produce insulin-like growth factor II (IGF-II), which acts by an autocrine mechanism to stimulate cell growth.
Leventhal, P S, Randolph, A E, Vesbit, T E, Schenone, A, Windebank, A, Feldman, E L   +5 more
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Insulin-like growth factor-II as a prognostic factor in pulmonary adenocarcinoma

Journal of Surgical Oncology, 1996
We stained resected specimens from 117 patients with pulmonary adenocarcinoma for insulin-like growth factor-II (IGF-II) by the avidin-biotin-peroxidase (ABC) method and evaluated the usefulness of IGF-II as a prognostic factor. The patients were classified into the IGF-II (+) groups showing staining of 1% or more cancer cells (60 patients) and the IGF-
I, Takanami, T, Imamuma, T, Hashizume, K, Kikuchi, Y, Yamamoto, T, Yamamoto, S, Kodaira   +6 more
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Insulin-Like Growth Factor-II and Insulin-Like Growth Factor-Binding Proteins in Bovine Cystic Ovarian Disease

Journal of Comparative Pathology, 2010
Cystic ovarian disease (COD) is one of the most common reproductive disorders of cattle and is considered to have multifactorial aetiology. An accepted hypothesis involves neuroendocrinological dysfunction of the hypothalamic-pituitary-gonadal axis; however, the role of growth factors in COD has not been extensively investigated.
F, Rey, F M, Rodríguez, N R, Salvetti, M M, Palomar, C G, Barbeito, N S, Alfaro, H H, Ortega   +6 more
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Insulin-Like Growth Factor-II

1994
A 67 amino acid peptide, structurally similar to IGF-I (somatomedin C), but having greater insulin-like activity, and less growth promoting activity. Both IGF-I and IGF-II share structural similarities with proinsulin.
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Insulin-like growth factor II in the rat choroid plexus

Molecular Brain Research, 1988
In situ hybridization histochemistry has been used to demonstrate the expression of the mRNA for insulin-like growth factor II (IGF-II) in the adult rat choroid plexus. IGF-II mRNA was found in the choroid plexus cells by using two different probes specific for different parts of IGF-II sequence.
Y, Ichimiya, P C, Emson, A J, Northrop, R S, Gilmour   +3 more
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Insulin-Like Growth Factor-II Receptors

1990
In the past few years there has been an explosive increase in interest in peptides of the insulin-like growth factor (IGF) family. This follows a period of over two decades, dating back to the discovery of “somatomedins,” as the IGFs were originally known, in the late 1950s.
Robert C. Baxter, Carolyn D. Scott
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Metabolic clearance of insulin-like growth factor-II in sheep

Journal of Endocrinology, 1989
ABSTRACT The metabolic clearance of ovine insulin-like growth factor-II (IGF-II) was examined in sheep using 131I-labelled IGF-II. Following i.v. administration the tracer was distributed in a volume similar to that of the vascular space (58-5 ±3.3 ml/kg; mean ± s.e.m., n = 5) and demonstrated a triphasic pattern of clearance.
S C, Hodgkinson, S R, Davis, L G, Moore, H V, Henderson, P D, Gluckman   +4 more
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