Results 141 to 150 of about 1,921,419 (361)

Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics

open access: yesAdvanced Functional Materials, EarlyView.
Designer DNA Architecture‐templated Drug Conjugates (DDA‐DCs) are comprised of a DNA nanomaterial decorated with multiple drug‐loaded DNA aptamers. DDA‐DCs use a combination of multiple aptamer types, each recognizing a different membrane protein to achieve precise targeting of cancer cells.
Abhisek Dwivedy   +19 more
wiley   +1 more source

Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin

open access: yesInternational Journal of Nanomedicine, 2018
You Xu,1,2 Xing Zhang,1,2 Yun Zhang,1,2 Jun Ye,1,2 Hong-Liang Wang,1,2 Xuejun Xia,1,2 Yuling Liu1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & ...
Xu Y   +6 more
doaj  

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Effects of feeding state on glycaemic and insulinaemic responses to a starchy meal in horses: a methodological approach

open access: yesAnimal, 2009
A standardised methodology is required for classification of starchy diets. One important question is what feeding status is optimal to describe glycaemic and insulinaemic responses to the respective starchy diet.
I. Vervuert, S. Klein, M. Coenen
doaj  

An AI-enabled dual-hormone model predictive control algorithm that delivers insulin and pramlintide [PDF]

open access: yesarXiv
Current closed-loop insulin delivery algorithms need to be informed of carbohydrate intake disturbances. This can be a burden on people using these systems. Pramlintide is a hormone that delays gastric emptying, which enables insulin kinetics to align with the kinetics of carbohydrate absorption.
arxiv  

Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels

open access: yesAdvanced Functional Materials, EarlyView.
A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco   +12 more
wiley   +1 more source

Glycemic Control among Pregnant Diabetic Women on Insulin Who Fasted During Ramadan [PDF]

open access: yesIranian Journal of Medical Sciences, 2011
Background: Ramadan fasting for pregnant women with diabetes remains controversial and underreported. The objective of this study was to determine the glycemic control in pregnant diabetic women on insulin who fasted during Ramadan.Methods: This was a ...
Nor Azlin Mohamed Ismail   +5 more
doaj  

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