Results 161 to 170 of about 1,879,389 (356)

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

Nature Reviews Neurology, 2018
S. Arnold, Zoe Arvanitakis, Shannon L. Macauley-Rambach, A. Koenig, Hoau Yan Wang, R. Ahima, S. Craft, S. Gandy, C. Buettner, L. Stoeckel, D. Holtzman, D. Nathan   +11 more
semanticscholar   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Insulin Bolus Patterns in Newly Diagnosed Youth With Type 1 Diabetes Using a Hybrid Closed-Loop Insulin Delivery System. [PDF]

J Diabetes Sci Technol
Royston C, Ware J, Allen JM, Wilinska ME, Hartnell S, Thankamony A, Randell T, Ghatak A, Besser REJ, Elleri D, Trevelyan N, Campbell FM, Hovorka R, Boughton CK, CLOuD Consortium.   +14 more
europepmc   +1 more source

Revealing the Dynamical Role of Co-solvents in the Coupled Folding and Dimerization of Insulin

, 2020
Xin‐Xing Zhang, Andrei Tokmakoff
openalex   +2 more sources

Modern strategies of alternative insulin delivery systems

, 2023
І. О. Власенко, Л. Л. Давтян, V. V. Hladyshev   +2 more
openalex   +2 more sources

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

From Pathophysiology to Treatment: Contemporary Approaches to CFRD in the Pediatric and Adolescent Population. [PDF]

Pediatr Diabetes
Vuralli D.
europepmc   +1 more source

Increased Extraocular Muscle Strength with Direct Injection of Insulin-like Growth Factor-I

, 2006
Brian C. Anderson, Stephen P. Christiansen, Steven Grandt, Robert W. Grange, Linda K. McLoon   +4 more
openalex   +2 more sources

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Molecular mechanism for pancreatic β-cell dysfunction and atherosclerosis. [PDF]

Diabetol Int
Kaneto H.
europepmc   +1 more source