Results 161 to 170 of about 2,129,772 (314)

Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion [PDF]

open access: bronze, 2007
Jingbo Pi   +10 more
openalex   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa   +7 more
wiley   +1 more source

Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis [PDF]

open access: hybrid, 2009
Naim Alkhouri   +7 more
openalex   +1 more source

Cyclic Peptide–Polymer Conjugate Nanotubes for Delivery of SN‐38 in Treatment of Colorectal Cancer Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops cyclic peptidepolymer conjugate nanotubes with hydrophobic, drug‐rich cores to enhance drug loading and stability, and demonstrates their responsive disassembly, pharmacokinetics, and anti‐tumour efficacy in colorectal cancer models using the anticancer drug SN‐38.
Sophie K. Hill   +4 more
wiley   +1 more source

Effectiveness of Gum Arabic With and Without Insulin on the Relieve of Some metabolic Complications of Diabetes Mellitus in Sprague-Dawley Rats

open access: yesJournal of Medical Sciences and Health, 2018
Background: This article aims to investigate the effect of gum Arabic dose with or without insulin on the expression of antioxidant and liver enzymes and the concentration of malondialdehyde (MDA), reduced glutathione (GSH), direct bilirubin, total ...
Mohammed Babiker   +4 more
doaj  

Preparation of Bifunctional Orthosilicophosphate MgO‐CaO‐ZnO‐P2O5‐SiO2 Glasses: in vitro Evaluation of Antibacterial Activity and Osteoblast Gene Expression Behavior

open access: yesAdvanced Healthcare Materials, EarlyView.
Bifunctional ZnO‐containing orthosilicophosphate glasses (SPGs) composed mainly of orthotetrahedral groups with the unique glass network structure without long‐chain units are prepared via melt‐quenching. The glasses exhibit excellent antibacterial activity and upregulate the expression of osteogenic markers by releasing inorganic ions.
Sungho Lee   +4 more
wiley   +1 more source

Improving global access to medicines for non-communicable diseases

open access: yesThe Lancet Global Health, 2014
David Beran   +3 more
doaj   +1 more source

A Non-Toxic Binuclear Vanadium(IV) Complex as Insulin Adjuvant Improves the Glycemic Control in Streptozotocin-Induced Diabetic Rats [PDF]

open access: gold
Mateus Santana Lopes   +13 more
openalex   +1 more source

Borate‐Ion‐Stimulated Macrophages Promote Osteogenic Differentiation of Mesenchymal Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
The immune responses of mouse macrophages stimulated by borate ions promote the osteogenic differentiation and mineralization of mouse bone marrow–derived mesenchymal stem cells in an ion‐dose‐dependent manner by providing cytokines, including BMP‐2.
Kazumasa Ikedo   +4 more
wiley   +1 more source

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