Results 181 to 190 of about 2,129,772 (314)

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Pathobiology of Prediabetes: Understanding and Interrupting Progressive Dysglycemia and Associated Complications. [PDF]

Diabetes
Dagogo-Jack S.
europepmc   +1 more source

The Effects of Different Exercises on Insulin Resistance and Testosterone Changes in Women with Polycystic Ovarian Syndrome: A Network Meta-Analysis Study [PDF]

Yong-Ming Tan, Yujie Liu, Ami Koga, Yuling Yuan, Haohan Yu, Jingmin Liu   +5 more
openalex   +1 more source

A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering

Advanced Healthcare Materials, EarlyView.
In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.
Bowu Peng, Huajian Chen, Chengyu Lu, Tianjiao Zeng, Man Wang, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen   +8 more
wiley   +1 more source

Combined Weight Loss and Exercise Training Alters Skeletal Muscle Subcellular Lipid Localization and Intermuscular Adipose Tissue Cellular Composition. [PDF]

Diabetes
Zemski Berry K, Garfield A, Whytock KL, Macias E, Zarini S, Jambal P, Stepaniak T, Bowen S, Perreault L, Johnson C, Kahn D, Kerege A, Tamburini IJ, Nguyen CM, Viesi CH, Seldin M, Sun Y, Walsh M, Sparks LM, Bergman BC.   +19 more
europepmc   +1 more source

Association of Insulin Resistance with Dysglycemia in Elder Koreans: Age- and Sex-Specific Cutoff Values [PDF]

Sang Min Yoon, Bo Young Park
openalex   +1 more source

Rates of Hypoglycemia Predicted in Patients with Type 2 Diabetes on Insulin Glargine 300 U/ml Versus First- and Second-Generation Basal Insulin Analogs: The Real-World LIGHTNING Study [PDF]

, 2019
Jeremy Pettus, Ronan Roussel, Fang Liz Zhou, Zsolt Bosnyák, Jukka Westerbacka, Rachele Berria, Javier Jiménez, Björn Eliasson, Irene Hramiak, Timothy S. Bailey, Luigi Meneghini   +10 more
openalex   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Effect of metformin on insulin resistance in adults with type 1 diabetes: a 26-week randomized double-blind clinical trial. [PDF]

Nat Commun
Snaith JR, Olsen N, Evans J, Kowalski GM, Bruce CR, Samocha-Bonet D, Breit SN, Holmes-Walker DJ, Greenfield JR.   +8 more
europepmc   +1 more source

P45 - Evaluating non-insulin-based metabolic markers for infertility risk assessment in women of reproductive age [PDF]

L. Kampanella, Loukas Charalambous
openalex   +1 more source