Results 221 to 230 of about 1,058,875 (320)

A comprehensive review on the implications of Yogic/Sattvic diet in reducing inflammation in type 2 diabetes. [PDF]

Nutr Diabetes
Vallazhath A, Thimmappa PY, Joshi HB, Hebbar KR, Nayak A, Umakanth S, Saoji AA, Manjunath NK, Hadapad BS, Joshi MB.   +9 more
europepmc   +1 more source

Tumor Microenvironment On‐A‐Chip and Single‐Cell Analysis Reveal Synergistic Stromal–Immune Crosstalk on Breast Cancer Progression

Advanced Science, EarlyView.
Using a 3D tumor microenvironment (TME)‐on‐a‐chip model, tumor–stromal–immune crosstalk in triple‐negative breast cancer is studied, revealing the TME's combinatorial effect on cancer progression. Integrating single‐cell transcriptomic analysis demonstrates metabolic reprogramming via the kynurenine pathway, highlighting the complex TME cellular ...
Kalpana Ravi, Yining Zhang, Lydia Sakala, Twinkle Jina Minette Manoharan, Barbara Pockaj, Joshua LaBaer, Jin G. Park, Mehdi Nikkhah   +7 more
wiley   +1 more source

Mettl3 deficiency leads to impaired insulin secretion via regulating Ire1a of mature β-cells in mice. [PDF]

Sci Rep
Zhang X, Shan A, Chen J, Cao Y, Jiang X.
europepmc   +1 more source

STUDIES ON THE SPECIFICITY OF AN INSULIN-INACTIVATING SYSTEM OF THE LIVER

, 1955
Henry H. Tomizawa, Robert H. Williams
openalex   +1 more source

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

Advanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu, Yaochang Wei, Yuelin Li, Yiming Dou, YongQiang Yang, Hanghang Liu, Xiaoyan Wang, Zheng Wang, Jianmin Su, Yong Zhang, Yongsheng Wang   +10 more
wiley   +1 more source

Immunotherapy as a treatment for type 1 diabetes mellitus in children and young adults: A comprehensive systematic review and meta-analysis. [PDF]

PLoS One
Salame G, Hakim V, Dagher C, Daou RM, Dada AE, Nassif L, Ghadieh HE, Azar S, Bazzi S, Harb F.   +9 more
europepmc   +1 more source

Microfluidics‐Based Microcarriers for Live‐Cell Delivery

Advanced Science, EarlyView.
In this review, recent advancements in microfluidics‐based microcarriers for live‐cell delivery are highlighted. The structural designs of microfluidic‐derived cell‐laden microcarriers are systematically categorized, emphasizing innovative approaches in the fabrication of microspheres, microfibers, and microneedles.
Zhonglin Fang, Xinyuan Yang, Chong Wang, Luoran Shang   +3 more
wiley   +1 more source

Rapid synthesis of glycosylated insulins by flow-based peptide synthesis. [PDF]

Chem Sci
Maki Y, Mong SK, Chandrashekar C, Forbes BE, Hossain MA, Yamaguchi S, Fadzen CM, Kajihara Y, Pentelute BL.   +8 more
europepmc   +1 more source

On the change in the nature of the blood sugar of diabetics caused by insulin

, 1923
W. Devereux Forrest, William E. Smith, L. B. Winter   +2 more
openalex   +2 more sources

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

Advanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang, Xiangxu Kong, Wei Wang, Huaxin Zhou, Haoran Qu, Zhengyao Guan, Honglei Wu, Xiangyu Zhai, Bin Jin   +8 more
wiley   +1 more source