Advanced Science, EarlyView.Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu +13 more
wiley +1 more source
Tight Glycemic Control Can Be Achieved in Adult ICU Patients Safely: Results From a 5-Year Single-Center Observational Study Using the STAR Glycemic Control Framework. [PDF]
J Diabetes Sci TechnolSeret M +4 more
europepmc +1 more source
Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy
Advanced Science, EarlyView.This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao +6 more
wiley +1 more source
Efficacy and safety of needle-free injection in patients with type 2 diabetes mellitus undergoing intensive insulin therapy: a randomized controlled trial based on the flash glucose monitoring system. [PDF]
Front Endocrinol (Lausanne)Wang J +12 more
europepmc +1 more source
Advanced Science, EarlyView.Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang +18 more
wiley +1 more source
16. Diabetes Care in the Hospital: Standards of Care in Diabetes-2026. [PDF]
Diabetes CareAmerican Diabetes Association Professional Practice Committee for Diabetes* .
europepmc +1 more source
Advanced Science, EarlyView.BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
Small Intestine-Targeted Long-Acting Oral Insulin Formulation Based on Engineered Milk Protein Nanoparticles. [PDF]
ACS Appl Bio MaterThamizhchelvan AM +9 more
europepmc +1 more source
The regulation of insulin-like growth factors in barramundi, Lates calcarifer [PDF]
, 1997 Sue Janet Matthews
openalex
CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human
Advanced Science, EarlyView.This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan +21 more
wiley +1 more source