Long-acting insulin allergy in a diabetic child [PDF]
International Journal of Immunopathology and Pharmacology, 2017 Insulin allergy has been uncommon since the introduction of human recombinant insulin preparations; the prevalence is 2.4%. Insulin injection could elicit immediate reactions, which are usually induced by an IgE-mediated mechanism, within the first hour ...
Carla Mastrorilli +5 more
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Case report: Insulin desensitization as the only option for managing insulin allergy in a Sudanese patient [PDF]
Frontiers in Allergy, 2023 IntroductionAllergic reactions to insulin have become very rare with the introduction of human insulin. Anaphylaxis is a life-threatening condition that results from immediate IgE-mediated hypersensitivity.
Rihan Said +4 more
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Insulin allergy can be successfully managed by a systematic approach [PDF]
Clinical and Translational Allergy, 2018 Background Type I insulin allergy can be a challenging condition, and there is no international consensus on how to establish the diagnosis. Measurement of specific IgE and skin testing have been cornerstones in the diagnostic work-up.
Maija Bruun Haastrup +3 more
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A pitfall in diagnosing type B insulin resistance syndrome: Suspected antibody interference in a patient with insulin allergy [PDF]
Journal of Diabetes InvestigationThe patient was a 73‐year‐old man with diabetes who developed marked hyperglycemia after several years of insulin therapy. Investigations showed marked hyperinsulinemia, positive insulin antibodies with low affinity/high binding capacity, insulin ...
Satoru Manda +4 more
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The complexities of insulin allergy: a case and approach [PDF]
Allergy, Asthma & Clinical Immunology, 2021 Background Insulin hypersensitivity is rare, but challenging for individuals with diabetes. The prevalence of insulin allergy has decreased since the introduction of human recombinant insulin preparations.
Babak Aberumand, Samira Jeimy
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Can a faulty injection technique lead to a localized insulin allergy?
Indian Journal of Endocrinology and Metabolism, 2013 Insulin allergy is a rare occurrence which can present diagnostic and management dilemmas for the clinician. Three types of reaction have been reported: Localized, generalized (systemic), and insulin resistance.
Trinanjan Sanyal +3 more
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Serious diabetic ketoacidosis induced by insulin allergy and anti‐insulin antibody in an individual with type 2 diabetes mellitus [PDF]
Journal of Diabetes Investigation, 2022 Diabetic ketoacidosis (DKA) is one of the most serious acute metabolic complications of diabetes mellitus, and is characterized by hyperglycemia, metabolic acidosis and increased total ketone body concentrations.
Kaio Takahashi +9 more
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Insulin Allergy to Detemir Followed by Rapid Onset of Diabetic Ketoacidosis: A Case Report and Literature Review [PDF]
Frontiers in Endocrinology, 2022 The management of diabetes mellitus in an insulin-dependent patient is challenging in the setting of concomitant antibody-mediated-insulin hypersensitivity.
Chong Boon Teo +14 more
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Successful management of severe diabetic ketoacidosis in a patient with type 2 diabetes with insulin allergy: a case report [PDF]
BMC Endocrine Disorders, 2019 Background Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that requires immediate treatment. Allergic reaction to insulin is rare, especially when using recombinant human insulin.
Anh Dat Nguyen +14 more
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Insulin allergy manifesting soon after COVID‐19 vaccination (BNT162b2) [PDF]
Journal of Diabetes Investigation, 2023 Hiroshi Komamura +3 more
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