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Case Report: Insulin hypersensitivity in youth with type 1 diabetes [PDF]
Frontiers in Endocrinology, 2023 ObjectiveImmediate type I, type III, and delayed type IV hypersensitivity reactions to insulin are rare, but potentially serious complications of exogenous insulin administration required for the treatment of type 1 diabetes (T1D).MethodsWe present four ...
Einas H. Alkhatib +12 more
doaj +5 more sources
Hypersensitivity reactions to human insulin analogs in insulin-naïve patients: a systematic review [PDF]
Therapeutic Advances in Endocrinology and Metabolism, 2018 Objective: The objective of this study was to raise awareness of hypersensitivity reactions to human insulin analogs (HIAs) in insulin-naïve patients and encourage consistent and detailed reporting of HIA reactions.
Andrew S. Bzowyckyj, Amanda M. Stahnke
doaj +6 more sources
Journal of the Formosan Medical Association, 2019 Although hypersensitivity reaction to insulin was supposed to be less-frequent with current insulin analogue, case reports with different types of allergic reactions to insulin analogue were still reported. The most common form is type I hypersensitivity
Wei-Lun Wen +6 more
doaj +4 more sources
A case report and systematic literature review: insulin-induced type III hypersensitivity reaction [PDF]
Frontiers in AllergyInsulin-induced type III hypersensitivity reactions (HSRs) are exceedingly rare and pose complex diagnostic and management challenges. We describe a case of a 43-year-old woman with type 1 diabetes mellitus (DM), severe insulin resistance, and ...
Rebecca R. Meredith +7 more
doaj +4 more sources
Frontiers in Endocrinology, 2022 The management of diabetes mellitus in an insulin-dependent patient is challenging in the setting of concomitant antibody-mediated-insulin hypersensitivity.
Chong Boon Teo +14 more
doaj +2 more sources
Case report: Insulin desensitization as the only option for managing insulin allergy in a Sudanese patient [PDF]
Frontiers in Allergy, 2023 IntroductionAllergic reactions to insulin have become very rare with the introduction of human insulin. Anaphylaxis is a life-threatening condition that results from immediate IgE-mediated hypersensitivity.
Rihan Said +4 more
doaj +2 more sources
A Case of Hypersensitivity to Soluble and Isophane Insulins but Not to Insulin Glargine.
Indian Journal of Pharmacology, 2015 Insulin is an important agent for the treatment of diabetes mellitus (DM). Allergic reactions to insulin therapy, although rare, have been evident since animal insulin became available for the treatment of DM in 1922. Hypersensitivity to insulin has considerably been reduced with the introduction of human insulin produced by recombinant ...
Renuka Munshi
exaly +4 more sources
Type III Hypersensitivity to Insulin Leading to Leukocytoclastic Vasculitis [PDF]
Diabetes Research and Clinical Practice, 2010 Here, we report the occurrence of leukocytoclastic vasculitis as an outcome of type III allergy to insulin in a patient with type II diabetes mellitus. The diagnosis was made on the basis of anatomo-pathological examination of a skin biopsy.
Eli Mansour, Ricardo de Lima Zollner
exaly +3 more sources
Student's Journal of Health Research Africa, 2023 BACKGROUND: Hypersensitivity to insulin is uncommon but difficult for diabetics. In light of the advancement of preparations containing human recombinant insulin, the incidence of insulin allergy has decreased. From erythema and edema at the site of the
Akhouri Sukrit Prakash
doaj +1 more source
Drosophila insulin receptor regulates diabetes-induced mechanical nociceptive hypersensitivity
microPublication Biology, 2021 Painful diabetic neuropathy (PDN) is one of the predominant complications of diabetes that causes numbness, tingling, and extreme pain sensitivity. Understanding the mechanisms of PDN pathogenesis is important for patient treatments.
Harika Dabbara +2 more
doaj +1 more source