Results 41 to 50 of about 7,548 (263)

Efficacy and Safety of Insulin Degludec/Insulin Aspart Compared with a Conventional Premixed Insulin or Basal Insulin: A Meta-Analysis

open access: yesMetabolites, 2021
Insulin degludec/insulin aspart (IDegAsp) is a novel co-formulation of 70% insulin degludec and 30% insulin aspart. The present meta-analysis was conducted to assess the efficacy and safety of IDegAsp compared with a conventional premixed insulin or ...
Shinje Moon   +6 more
doaj   +1 more source

Pragmatic use of insulin degludec/insulin aspart co-formulation: A multinational consensus statement

open access: yesIndian Journal of Endocrinology and Metabolism, 2016
Insulin degludec/insulin aspart (IDegAsp) is a modern coformulation of ultra-long-acting basal insulin degludec, with rapid-acting insulin aspart. IDegAsp provides effective, safe, well-tolerated glycemic control, with a low risk of hypoglycemia while ...
Sanjay Kalra   +6 more
doaj   +1 more source

Cost-effectiveness of insulin degludec versus insulin glargine U100 in adults with type 1 and type 2 diabetes mellitus in Bulgaria

open access: yesBMC Endocrine Disorders, 2019
Background This analysis evaluates the cost-effectiveness of insulin degludec (degludec) versus biosimilar insulin glargine U100 (glargine U100) in patients with type 1 (T1DM) and type 2 diabetes mellitus (T2DM) in Bulgaria.
Monika Russel-Szymczyk   +3 more
doaj   +1 more source

Efficacy and safety of insulin degludec in renal transplant recipients with pre-existing diabetes

open access: yesEndocrine and Metabolic Science, 2021
Introduction: Glycemic control is important in renal transplant receptions with diabetes. In the early post-transplant period, recovering renal function and concomitant steroids and immunosuppressants increase the risk of dysglycemia which adversely ...
Debmalya Sanyal   +2 more
doaj   +1 more source

Effect of insulin glargine on cardiovascular risk analysed by mean HRV [PDF]

open access: yes, 2019
Type 2 diabetes mellitus is an insidious disease that is increasingly present in geriatric population [1]. The greatest difficulty is represented by glycaemic control in geriatric patients often not very compliant with diet therapy and drug therapy.
Apicella, G.   +5 more
core   +1 more source

Continuous subcutaneous insulin infusion therapy and multiple daily insulin injections in type 1 diabetes mellitus: a comparative overview and future horizons. [PDF]

open access: yes, 2015
INTRODUCTION: Continuous subcutaneous insulin infusion (CSII) therapy is currently accepted as a treatment strategy for type 1 diabetes. Transition from multiple daily injection therapy (MDI; including basal-bolus regimens) to CSII is based on ...
Hovorka, R, Mohd-Thabit, HA
core   +1 more source

Efficacy and hypoglycaemia outcomes of once‐weekly insulin icodec versus once‐daily basal insulin comparators across baseline HbA1c, BMI and duration of type 2 diabetes subgroups: A post hoc analysis of ONWARDS 1–5

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This post hoc analysis assessed efficacy and hypoglycaemia outcomes of once‐weekly insulin icodec (icodec) versus once‐daily (OD) basal insulin comparators across different baseline glycated haemoglobin (HbA1c), body mass index (BMI) and type 2 diabetes (T2D) duration subgroups using data from five phase 3a trials of icodec in adults with
Alice Y. Y. Cheng   +5 more
wiley   +1 more source

THE USE OF ULTRA-LONG-ACTING INSULIN ANALOGUE DEGLUDEC IN TYPE 1 DIABETES MELLITUS IN CLINICAL PRACTICE: THE INFLUENCE ON QUALITY OF LIFE AND SATISFACTION WITH TREATMENT

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
Background: Maintenance of stable glycemic control is an important prerequisite of effective treatment of patients with type 1 diabetes mellitus (DM).
M. F. Kalashnikova   +6 more
doaj   +1 more source

Insulin therapy DE‐intensificAtion with iGlarLixi: A phase 4, open‐label, parallel‐group randomised controlled trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To evaluate the efficacy and safety of transitioning from multiple daily injections (MDIs) insulin regimen to once‐daily, fixed‐ratio combination of basal insulin analog glargine 100 U/mL and a glucagon‐like peptide 1 receptor agonist lixisenatide (iGlarLixi) in people with type 2 diabetes (PwT2D). Materials and Methods Insulin therapy DE‐
Peter Novodvorský   +14 more
wiley   +1 more source

Basal insulin analogues in the treatment of diabetes mellitus: What progress have we made?

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Over the past few decades, continuous progress has been made in the development of insulin therapy. Basal insulins were developed around 60 years ago. However, existing basal insulins were found to have limitations. An ideal basal insulin should have the
Sanjay Kalra
doaj   +1 more source

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