Results 41 to 50 of about 411,749 (186)
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley +1 more source
Long-acting insulin allergy in a diabetic child
Insulin allergy has been uncommon since the introduction of human recombinant insulin preparations; the prevalence is 2.4%. Insulin injection could elicit immediate reactions, which are usually induced by an IgE-mediated mechanism, within the first hour ...
Carla Mastrorilli +5 more
doaj +1 more source
Effects of insulin and analogues on carcinogen-induced mammary tumours in high-fat-fed rats
It is not fully clarified whether insulin glargine, an analogue with a high affinity for insulin-like growth factor-1 receptor (IGF-1R), increases the risk for cancers that abundantly express IGF-1R such as breast cancer or some types of breast cancer ...
Yusaku Mori +8 more
doaj +1 more source
The Effect of Basal Analog Insulin on the Glycemic Variability in Type 2 Diabetics
Purpose: The aim of this study was to investigate the effect of insulin detemir and glargine on glycemic variability as determined by capillary blood glucose measurements in Type 2 diabetics treated with oral antidiabetic drugs.
Soner Cander +4 more
doaj +1 more source
In Ontario, biologics have historically represented a small proportion of public drug claims but a large proportion of spending. Biosimilars, lower cost alternatives to biologics, offer a potential solution to the rising spending on biologics. From March 2023 to January 2024, the Ontario Ministry of Health required public drug program beneficiaries on ...
Anita Iacono +10 more
wiley +1 more source
Insulin detemir versus insulin glargine for type 2 diabetes mellitus
Chronically elevated blood glucose levels are associated with significant morbidity and mortality. Many diabetes patients will eventually require insulin treatment to maintain good glycaemic control.
Hoekstra, Joost B. +4 more
core +1 more source
Maternal diabetes impairs fetal lung maturation, creating subclinical respiratory risks at birth. The study compared 37 newborns of diabetic mothers against 40 healthy controls using cord blood analysis and tidal breath measurements. Results showed elevated leptin alongside decreased ghrelin and adiponectin levels.
Simge Atar Bese +9 more
wiley +1 more source
Abstract Aims Research to inform, co‐develop and evaluate optimal care for women with early‐onset type 2 diabetes (EOT2D) before, during and after pregnancy is lacking. Informed by patient perspectives and the results of the James Lind Alliance priority‐setting partnership in diabetes in pregnancy, we aimed to develop a consensus statement to guide ...
Sara L. White +8 more
wiley +1 more source
All patients with Diabetes Mellitus (DM) receive insulin therapy. In this study, we evaluated the efficacy, safety and tolerability of human insulin and insulin analogues.
Andréia Cristina Conegero Sanches +6 more
doaj +1 more source
Abstract Objective To comprehensively assess the cost‐utility of icodec, the first once‐weekly basal insulin, at 700 and 1050 U formulations compared with once‐daily basal insulin analogues in Chinese adults with type 2 diabetes within reimbursement context.
Xichen Tong +3 more
wiley +1 more source

