Results 51 to 60 of about 7,984 (250)
Effects of insulin and analogues on carcinogen-induced mammary tumours in high-fat-fed rats
Endocrine Connections, 2018 It is not fully clarified whether insulin glargine, an analogue with a high affinity for insulin-like growth factor-1 receptor (IGF-1R), increases the risk for cancers that abundantly express IGF-1R such as breast cancer or some types of breast cancer ...
Yusaku Mori +8 more
doaj +1 more source
The management of type 1 and type 2 diabetes in pregnancy [PDF]
, 2015 Pregestational diabetes is a common medical complication of pregnancy and preconception planning is an essential component of care for affected women of childbearing age.
Dunne, F P, Egan, A M, Murphy, H R
core +1 more source
Diabetic Medicine, Volume 43, Issue 2, February 2026.Abstract Aim Type 2 diabetes (T2D) in pregnancy is increasingly common and associated with suboptimal outcomes for these women and their children. We aimed to synthesize observational evidence on associations of modifiable preconception, pregnancy and postpartum risk factors with perinatal outcomes among women with pregestational T2D.
Danielle Schoenaker +11 more
wiley +1 more source
Detemir as a once-daily basal insulin in type 2 diabetes
Clinical Pharmacology: Advances and Applications, 2011 Scott E NelsonCleveland Family Medicine, Cleveland, Mississippi, USABackground: Insulin detemir, a long-acting basal insulin analog, is labeled for once-daily or twice-daily dosing in patients with type 1 (T1DM) or type 2 (T2DM) diabetes mellitus ...
Nelson SE
doaj
Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan +6 more
wiley +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2013 All patients with Diabetes Mellitus (DM) receive insulin therapy. In this study, we evaluated the efficacy, safety and tolerability of human insulin and insulin analogues.
Andréia Cristina Conegero Sanches +6 more
doaj +1 more source
Very tight vs. tight control: what should be the criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy? Evidence from randomized controlled trials [PDF]
, 2017 INTRODUCTION: There is inconclusive evidence from randomized controlled trials (RCTs) to support any specific criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy.
Berghella, Vincenzo +3 more
core +1 more source
A Rational Approach to Pharmacotherapy in Pregnancy
The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen +2 more
wiley +1 more source
Analisis Efektivitas Biaya Penggunaan Terapi Kombinasi Insulin dan Oho pada Pasien Diabetes Melitus Tipe 2 Rawat Jalan di RSUD Wangaya [PDF]
, 2013 Bervariasinya penggunaan terapi insulin tunggal atau kombinasi insulin dengan Obat Hipoglikemik Oral (OHO) pada pasien DM tipe 2 dengan kontrol glukosa darah yang belum adekuat akan mengakibatkan adanya perbedaan dalam biaya dan efektivitas terapinya ...
Febryana L, Luh Putu +2 more
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Euglycemic Diabetic Ketoacidosis in Concurrent Very Low-carbohydrate Diet and Sodium-glucose Transporter-2 Inhibitor Use: A Case Report [PDF]
, 2020 Introduction: With the incredibly high incidence of Type 2 Diabetes in the current population of emergency department patients, it is critical for clinicians to understand the possible complications of the treatment of this disease.
Ault, Brian +2 more
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