Results 61 to 70 of about 7,984 (250)

Projected long-term outcomes in patients with type 1 diabetes treated with fast-acting insulin aspart versus conventional insulin aspart in the UK setting [PDF]

, 2017
Aims: Many patients with type 1 diabetes mellitus (T1DM) fail to achieve optimal glycemic control and mealtime insulins that more closely match physiological insulin secretion can help improve treatment.
Buchs, S., Heller, S., Hunt, B., Russell-Jones, D., Sandberg, A., Valentine, W.J.   +5 more
core   +1 more source

Emulating a Randomized Controlled Trial of Long‐Acting Insulins and Cardiovascular Events Using Real‐World Data for Patients With Type 2 Diabetes

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 1, January 2026.
ABSTRACT Aims Randomized controlled trials (RCTs) have high internal validity but often have limited generalizability. To our knowledge, there have been no previous studies emulating RCTs using real‐world data to evaluate the risk of major adverse cardiovascular events (MACE) among patients with type 2 diabetes mellitus (T2DM) treated with long‐acting ...
Wanning Wang, Pauline Reynier, Michael Webster‐Clark, Oriana H. Y. Yu, Vanessa Brunetti, Kristian B. Filion   +5 more
wiley   +1 more source

Tolerability, safety and adherence to treatment with insulin detemir injection in the treatment of type 2 diabetes

Patient Preference and Adherence, 2008
Athena Philis-TsimikasScripps Whittier Diabetes Institute, La Jolla, CA, USAAbstract: The progressive nature of type 2 diabetes poses challenges in the clinic: treatment must be continually reviewed and adjusted in response to the patient’s ...
Athena Philis-Tsimikas
doaj  

Enhanced Radionuclide Therapy via the Conjugation of Pentadecanoic Acids With 225Ac‐ and 177Lu‐Labeled RGD Peptides

Cancer Science, Volume 117, Issue 1, Page 193-202, January 2026.
Radionuclide therapy using PD‐K(225Ac‐DOTA)‐RGD in BxPC‐3‐bearing mice. PD‐K(225Ac‐DOTA)‐RGD successfully suppressed tumor growth. ABSTRACT Improved peptide pharmacokinetics are needed to enhance the therapeutic effects of peptide‐based radionuclide therapy.
Mitsuyoshi Yoshimoto, Shun‐ichi Wada, Yukie Yoshii, Sayaka Hanadate, Anri Inaki, Hirofumi Fujii   +5 more
wiley   +1 more source

Initiation of Hybrid Closed‐Loop Artificial Pancreas System Improves Glycemic Control in a Hospitalized Type 1 Diabetes: A Case Report and Review

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Background To observe the efficacy and safety of artificial pancreas (Android‐hybrid closed‐loop [HCL] system) in patients with type 1 diabetes mellitus (T1DM), and to compare it with insulin multi‐injection therapy. Case presentation A patient with long course of type 1 diabetes was treated with multiple injections of insulin, Android‐HCL therapy, and
Shaohua Li, Pin Lv, Haosi Lu, Yang Liu, Yang Shen, Cijing Cai, Xifeng Zeng, Hongyun Lu, Yu Zhao, Kalyani Sen   +9 more
wiley   +1 more source

Cost-effectiveness of insulin analogs from the perspective of the Brazilian public health system

Brazilian Journal of Pharmaceutical Sciences, 2017
Human insulin is provided by the Brazilian Public Health System (BPHS) for the treatment of diabetes, however, legal proceedings to acquire insulin analogs have burdened the BPHS health system.
Maurílio de Souza Cazarim, João Paulo Vilela Rodrigues, Estael Luzia Coelho da Cruz-Cazarim, Lorena Rocha Ayres, Leonardo Régis Leira Pereira   +4 more
doaj   +1 more source

Continuous subcutaneous insulin infusion therapy and multiple daily insulin injections in type 1 diabetes mellitus: a comparative overview and future horizons. [PDF]

, 2015
INTRODUCTION: Continuous subcutaneous insulin infusion (CSII) therapy is currently accepted as a treatment strategy for type 1 diabetes. Transition from multiple daily injection therapy (MDI; including basal-bolus regimens) to CSII is based on ...
Hovorka, R, Mohd-Thabit, HA
core   +1 more source

Optimizing adipogenic transdifferentiation of bovine mesenchymal stem cells: a prominent role of ascorbic acid in FABP4 induction [PDF]

, 2020
Adipocyte differentiation of bovine adipose-derived stem cells (ASC) was induced by foetal bovine serum (FBS), biotin, pantothenic acid, insulin, rosiglitazone, dexamethasone and 3-isobutyl-1-methylxanthine, followed by incubation in different media to ...
Aschenbach, Jörg R., Bermúdez- Peña, M. Carmen, Jurek, Sandra, Kolisek, Martin, Sandhu, Mansur A., Sponder, Gerhard, Trappe, Susanne   +6 more
core   +1 more source

Characteristics Relating to Adherence and Persistence to Basal Insulin Regimens Among Elderly Insulin-Naïve Patients with Type 2 Diabetes: Pre-Filled Pens versus Vials/Syringes [PDF]

, 2015
INTRODUCTION: Previous studies have found higher rates of adherence in patients with type 2 diabetes mellitus (T2DM) using insulin pens compared to vial and syringe administration; however, little evidence is available to support this observation in ...
D. Chad Moretz, Jean C. Baltz, Jonathan R. Bouchard, S. Lane Slabaugh, Yong Li, Yunus A. Meah   +5 more
core   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source