Results 161 to 170 of about 123,332 (229)

Metabolic perturbations in Welsh Ponies with insulin dysregulation, obesity, and laminitis. [PDF]

J Vet Intern Med, 2018
Jacob SI, Murray KJ, Rendahl AK, Geor RJ, Schultz NE, McCue ME.   +5 more
europepmc   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

Sweet taste receptor inhibitors: Potential treatment for equine insulin dysregulation. [PDF]

PLoS One, 2018
de Laat MA, Kheder MH, Pollitt CC, Sillence MN.   +3 more
europepmc   +1 more source

Roles of histone lysine methylation in neurodevelopment and related disorders

Ibrain, EarlyView.
This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen, Yi Zhang, Hong Zhang, Xiaoli Liang   +3 more
wiley   +1 more source

Rising Incidence and Mortality of Colorectal Cancer Among Younger Adults: A Population‐Based Study in Taiwan, 1994–2018

International Journal of Cancer, EarlyView.
Colorectal cancer incidence and mortality have increased in the Asia‐Pacific region over the past three decades. This population‐based study in Taiwan suggests a shift of the colorectal cancer burden towards the younger generations. An age–period–cohort model revealed higher annual increases in incidence (3.58%) and mortality (1.0%) rates among ...
Yun‐Chen Tsai, Chih‐Yi Wu, Tsung‐I Hung, Hung‐Yi Chiou   +3 more
wiley   +1 more source

Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease. [PDF]

Neurobiol Aging, 2017
Velazquez R, Tran A, Ishimwe E, Denner L, Dave N, Oddo S, Dineley KT.   +6 more
europepmc   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source

Surgically confirmed severe endometriosis is associated with lower risk of steatotic liver disease: Evidence of estrogen‐linked hepatic–reproductive crosstalk

International Journal of Gynecology &Obstetrics, EarlyView.
Severe surgically confirmed endometriosis was associated with a lower prevalence of steatotic liver disease than non‐severe disease. Higher estradiol levels may partly explain this inverse hepatic–reproductive association, supporting integrated gynecologic and hepatologic risk assessment.
Jung Hyun Park, Keungmo Yang, Hyun Yang, Si Hyun Bae, Mee‐Ran Kim, Jaejun Lee   +5 more
wiley   +1 more source

Associations of C‐Reactive Protein–Triglyceride–Glucose Index With the Incidence and Progression of Cardiometabolic Multimorbidity in Middle‐Aged and Older Chinese Individuals: A Prospective Cohort Study From CHARLS

iLABMED, EarlyView.
This study investigated the association between C‐reactive protein‐triglyceride‐glucose index (CTI) and cardiometabolic multimorbidity (CMM) over a 9‐year follow‐up in a Chinese middle‐aged and older population. Higher CTI levels were significantly associated with an increased risk of CMM.
Zhengfeng Wu, Honghong Zhang, Yajun Zheng, Haijing Zhao, Jie Liu, Yuhan Ma, Yuqi Liu   +6 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source