Results 201 to 210 of about 123,332 (229)
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Insulin signaling in insulin-dysregulated Icelandic horses
Domestic Animal EndocrinologyThe underlying molecular mechanisms leading to insulin dysregulation are poorly understood in horses. Therefore, this study aimed to determine if insulin dysregulation is associated with an altered basal expression and extent of phosphorylation of key proteins of the insulin signaling cascade in liver (LT), muscle (MT), and subcutaneous adipose tissue (
F. Frers +4 more
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Equine Veterinary Journal
Abstract Background It is unknown whether short‐term transportation affects endocrine responses similarly in horses with and without insulin dysregulation (ID). Objectives To characterise the effect of short‐term ...
Erica T. Jacquay +2 more
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Abstract Background It is unknown whether short‐term transportation affects endocrine responses similarly in horses with and without insulin dysregulation (ID). Objectives To characterise the effect of short‐term ...
Erica T. Jacquay +2 more
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Insulin Resistance Syndrome and Glucose Dysregulation in the Elderly
Clinics in Geriatric Medicine, 2008The incidence of insulin resistance in the geriatric population is growing as this population grows. The management of hyperglycemia and its associated risk factors depends on an expanding understanding of the underlying pathophysiology and progression of disease and of the currently available and future therapeutics, which are continually evolving ...
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Seasonal Insulin Responses to the Oral Sugar Test in Healthy and Insulin Dysregulated Horses
Journal of Equine Veterinary Science, 2021Seasonal effects on the oral sugar test (OST), used to monitor insulin dysregulation (ID) status to help reduce laminitis risk, are poorly understood in the ID horse. Resting, (basal) insulin (T0) and 60-minute (T60) OST (0.15 mL/Kg BW Karo Light Corn Syrup) insulin responses were evaluated, once per each season over 2 years, in ID (n = 11 14.9 ± 4.3 ...
Erica Lyn Macon +3 more
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Inflammation and Insulin Dysregulation in the Horse
2017Insulin dysregulation (ID) in the horse is receiving increasing attention as a serious health concern, in particular due to its association with the potentially career or life ending condition, laminitis. The role of inflammation and the immune system in ID as well as its associated health concerns has also been raised.
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BCAA Metabolism and Insulin Sensitivity – Dysregulated by Metabolic Status?
Molecular Nutrition & Food Research, 2018AbstractBranched‐chain amino acids (BCAAs) appear to influence several synthetic and catabolic cellular signaling cascades leading to altered phenotypes in mammals. BCAAs are most notably known to increase protein synthesis through modulating protein translation, explaining their appeal to resistance and endurance athletes for muscle hypertrophy ...
Nicholas P, Gannon +2 more
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Brain Insulin Dysregulation: Implication for Neurological and Neuropsychiatric Disorders
Molecular Neurobiology, 2013Arduous efforts have been made in the last three decades to elucidate the role of insulin in the brain. A growing number of evidences show that insulin is involved in several physiological function of the brain such as food intake and weight control, reproduction, learning and memory, neuromodulation and neuroprotection.
Rasoul, Ghasemi +5 more
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Insulin dysregulated horses metabolic responses to forage pellets
Journal of Equine Veterinary ScienceHyperinsulinemia-associated laminitis (HAL) is the primary concern for insulin dysregulated (ID) equids and their insulin response to the consumption of oral, nonstructural carbohydrates (NSC) has been shown to be a risk predictor for HAL development.
Erica Lyn Macon +4 more
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