Results 201 to 210 of about 134,602 (231)

Lipid and lipoprotein dysregulation in insulin resistant states

Clinica Chimica Acta, 2006
Insulin resistant states are commonly associated with an atherogenic dyslipidemia that contributes to significantly higher risk of atherosclerosis and cardiovascular disease. Indeed, disorders of carbohydrate and lipid metabolism co-exist in the majority of subjects with the "metabolic syndrome" and form the basis for the definition and diagnosis of ...
Rita Kohen, Avramoglu, Heather, Basciano, Khosrow, Adeli   +2 more
openaire   +2 more sources

Insulin signaling in insulin-dysregulated Icelandic horses

Domestic Animal Endocrinology
The underlying molecular mechanisms leading to insulin dysregulation are poorly understood in horses. Therefore, this study aimed to determine if insulin dysregulation is associated with an altered basal expression and extent of phosphorylation of key proteins of the insulin signaling cascade in liver (LT), muscle (MT), and subcutaneous adipose tissue (
F. Frers, J. Delarocque, K. Feige, K. Huber, T. Warnken   +4 more
openaire   +2 more sources

The impact of short‐term transportation stress on insulin and oral sugar responses in insulin dysregulated and non‐insulin dysregulated horses

Equine Veterinary Journal
Abstract Background It is unknown whether short‐term transportation affects endocrine responses similarly in horses with and without insulin dysregulation (ID). Objectives To characterise the effect of short‐term ...
Erica T. Jacquay, Patricia A. Harris, Amanda A. Adams   +2 more
openaire   +2 more sources

Insulin Resistance Syndrome and Glucose Dysregulation in the Elderly

Clinics in Geriatric Medicine, 2008
The incidence of insulin resistance in the geriatric population is growing as this population grows. The management of hyperglycemia and its associated risk factors depends on an expanding understanding of the underlying pathophysiology and progression of disease and of the currently available and future therapeutics, which are continually evolving ...
openaire   +2 more sources

Insulin resistance and SIRT1 dysregulation in neurodegenerative diseases

Ageing Research Reviews
Metabolic diseases such as Type 2 Diabetes, obesity, and metabolic syndrome are increasing worldwide in parallel with neurodegenerative disorders, yet a unifying biological framework linking systemic metabolic dysfunction to progressive neuronal loss is still lacking.
Anery Shah, Gaurav Doshi
openaire   +2 more sources

Inflammation and Insulin Dysregulation in the Horse

2017
Insulin dysregulation (ID) in the horse is receiving increasing attention as a serious health concern, in particular due to its association with the potentially career or life ending condition, laminitis. The role of inflammation and the immune system in ID as well as its associated health concerns has also been raised.
openaire   +1 more source

Brain Insulin Dysregulation: Implication for Neurological and Neuropsychiatric Disorders

Molecular Neurobiology, 2013
Arduous efforts have been made in the last three decades to elucidate the role of insulin in the brain. A growing number of evidences show that insulin is involved in several physiological function of the brain such as food intake and weight control, reproduction, learning and memory, neuromodulation and neuroprotection.
Rasoul, Ghasemi, Leila, Dargahi, Ali, Haeri, Maryam, Moosavi, Zahurin, Mohamed, Abolhassan, Ahmadiani   +5 more
openaire   +2 more sources

BCAA Metabolism and Insulin Sensitivity – Dysregulated by Metabolic Status?

Molecular Nutrition & Food Research, 2018
AbstractBranched‐chain amino acids (BCAAs) appear to influence several synthetic and catabolic cellular signaling cascades leading to altered phenotypes in mammals. BCAAs are most notably known to increase protein synthesis through modulating protein translation, explaining their appeal to resistance and endurance athletes for muscle hypertrophy ...
Nicholas P, Gannon, Jamie K, Schnuck, Roger A, Vaughan   +2 more
openaire   +2 more sources

Review for "Postprandial insulin responses to various feedstuffs differ in insulin dysregulated horses compared to non‐insulin dysregulated controls"

2021
  +5 more sources

Insulin dysregulated horses metabolic responses to forage pellets

Journal of Equine Veterinary Science
Hyperinsulinemia-associated laminitis (HAL) is the primary concern for insulin dysregulated (ID) equids and their insulin response to the consumption of oral, nonstructural carbohydrates (NSC) has been shown to be a risk predictor for HAL development.
Erica Lyn Macon, Patricia Harris, Margaret McClendon, Brittany Perron, Amanda Adams   +4 more
openaire   +2 more sources