Results 31 to 40 of about 242,514 (346)

The Melanocortin-4 Receptor Integrates Circadian Light Cues and Metabolism [PDF]

, 2015
The melanocortin system directs diverse physiological functions from coat color to body weight homoeostasis. A commonality among melanocortin-mediated processes is that many animals modulate similar processes on a circannual basis in response to longer ...
Arble, Deanna M., Herman, James P., Holland, Jenna, Morano, Rachel, Ottaway, Nickki, Perez-Tilve, Diego, Pressler, Joshua W., Sandoval, Darleen A., Seeley, Randy J., Sorrell, Joyce, Woods, Stephen C.   +10 more
core   +2 more sources

The effects of peripheral and central high insulin on brain insulin signaling and amyloid-β in young and old APP/PS1 mice [PDF]

, 2016
Hyperinsulinemia is a risk factor for late-onset Alzheimer's disease (AD). In vitro experiments describe potential connections between insulin, insulin signaling, and amyloid-β (Aβ), but in vivo experiments are needed to validate these relationships ...
Caesar, Emily E, Holtzman, David M, Jiang, Hong, Keyser, Jennifer, Koscal, Lauren J, Macauley, Shannon L, Moritz, Will, Robinson, Grace O, Roh, Joseph, Stanley, Molly   +9 more
core   +2 more sources

A randomised controlled study of high intensity exercise as a dishabituating stimulus to improve hypoglycaemia awareness in people with type 1 diabetes:a proof of concept study [PDF]

, 2020
Aims/hypothesis Approximately 25% of people with type 1 diabetes have suppressed counterregulatory hormonal and symptomatic responses to insulin-induced hypoglycaemia, which renders them at increased risk of severe, disabling hypoglycaemia.
Farrell, Catriona M., Fournier, Paul, Hapca, Simona M., Jones, Timothy, McCrimmon, Rory J., McNeilly, Alison D., West, Daniel   +6 more
core   +4 more sources

Insulin therapy and dietary adjustments to normalize glycemia and prevent nocturnal hypoglycemia after evening exercise in type 1 diabetes: a randomized controlled trial [PDF]

, 2014
Introduction Evening-time exercise is a frequent cause of severe hypoglycemia in type 1 diabetes, fear of which deters participation in regular exercise.
Campbell, Matthew, Walker, Mark, Bracken, Richard, Turner, David, Stevenson, Emma, Gonzalez, Javier, Shaw, James, West, Dan   +7 more
core   +4 more sources

Intravenous insulin infusion system to determine insulin regimen in diabetics.

The Tohoku Journal of Experimental Medicine, 1988
An algorithm for insulin infusion system to control blood glucose was derived from results of intravenous (i.v.) insulin infusion performed on 10 diabetics. I.v. insulin infusion was done on 14 diabetics for 24 hr using the algorithm, and blood glucose was controlled within the proper range in all cases; mean blood glucose was 130 +/- 42 mg/100 ml ...
M, Ito, T, Sato, T, Saito, M, Kokubun, M, Inoue, K, Saito, K, Yoshinaga   +6 more
openaire   +3 more sources

The role of technology in the care of diabetes mellitus in pregnancy: an expert review

AJOG Global Reports, 2023
Diabetes mellitus is one of the most commonly encountered pregnancy complications and is associated with multiple adverse perinatal outcomes. Technology has progressed to address the unique challenges patients face in managing diabetes mellitus in ...
Sydney M. Thayer, MD, Kelley J. Williams, MD, Megan L. Lawlor, MD   +2 more
doaj   +1 more source

Accuracy assessment of bolus and basal rate delivery of different insulin pump systems used in insulin pump therapy of children and adolescents

Pediatric Diabetes, 2020
Continuous subcutaneous insulin infusion (CSII) is commonly used in patients with diabetes. Accurate and reliable delivery by insulin pumps is essential for a safe and effective therapy, particularly when using small doses.
R. Ziegler, D. Waldenmaier, U. Kamecke, J. Mende, Cornelia Haug, G. Freckmann   +5 more
semanticscholar   +1 more source

Use of continuous subcutaneous insulin infusion by a portable insulin pump during pregnancy in women with type 1 diabetes mellitus [PDF]

Vojnosanitetski Pregled, 2006
Background/aim: Diabetes mellitus is associated with an increased risk for neonatal morbidity and mortality. One of the most important goals in treating pregnancies complicated with diabetes is keeping glucose level within the normal range, especially in
Zorić Svetlana, Micić Dragan, Kendereški Aleksandra, Šumarac-Dumanović Mirjana, Cvijović Goran, Pejković Danica, Cvetković Miloš, Ljubić Aleksandar, Dukanac-Stamenković Jelena   +8 more
doaj   +1 more source

Nano-Amounts of Glucagon Premixed With Fast-Acting Insulin Lispro: Effect on Insulin Absorption in Pigs

Current Therapeutic Research
Background: Glucagon leads to substantial but short-lived subcutaneous vasodilation. Using micro-amounts of glucagon at the insulin injection site increases insulin absorption.
Ilze Dirnena-Fusini, PhD, Misbah Riaz, MSc, Sverre Christian Christiansen, MD, PhD, Sven Magnus Carlsen, MD, PhD   +3 more
doaj   +1 more source

Continuous Glucose Monitoring Sensors for Diabetes Management: A Review of Technologies and Applications [PDF]

Diabetes & Metabolism Journal, 2019
By providing blood glucose (BG) concentration measurements in an almost continuous-time fashion for several consecutive days, wearable minimally-invasive continuous glucose monitoring (CGM) sensors are revolutionizing diabetes management, and are ...
Giacomo Cappon, Martina Vettoretti, Giovanni Sparacino, Andrea Facchinetti   +3 more
doaj   +1 more source