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BACE1 Inhibition Protects Against Type 2 Diabetes Mellitus by Restoring Insulin Receptor in Mice. [PDF]
Lin T, Liang T, Shen Y, Gao F.
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TRIM32 regulates insulin sensitivity by controlling insulin receptor degradation in the liver. [PDF]
Thakur S, Rawat P, Dehury B, Mondal P.
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Worse survival of hepatocellular cancer patients with membranous insulin receptor overexpression. [PDF]
Heckl SM +12 more
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Activation of the Insulin Receptor by <i>Sarcopoterium spinosum</i> Extract and Identification of Sarcocyanidin A as a Novel Active Compound. [PDF]
Wollman A +3 more
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[Insulin and insulin receptor disorders].
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Insulin, insulin receptors, and cancer
Journal of Endocrinological Investigation, 2016Insulin is a major regulator of cell metabolism but, in addition, is also a growth factor. Insulin effects in target cells are mediated by the insulin receptor (IR), a transmembrane protein with enzymatic (tyrosine kinase) activity. The insulin receptor, however, is represented by a heterogeneous family of proteins, including two different IR isoforms ...
Vigneri R +2 more
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