Results 291 to 300 of about 794,012 (351)

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source

THE NEUROPEPTIDE NEUROMEDIN U RECEPTOR NMUR-1 BUFFERS INSULIN RECEPTOR SIGNALING IN BACTERIA-DEPENDENT C. ELEGANS SURVIVAL

Sifoglu D, Pereira B, DeGregory C, Shah R, Maier W, Guan J, Clark I, Patel D, Ch’ng Q, Alcedo J.   +9 more
europepmc   +1 more source

Uncovering the function of insulin receptor substrate in termites' immunity through active immunization. [PDF]

J Insect Sci
Zhou W, Zhao X, Hassan A, Jia B, Liu L, Huang Q.   +5 more
europepmc   +1 more source

Correction to: "Insulin Signaling Through the Insulin Receptor Increases Linear Growth Through Effects on Bone and the GH-IGF-1 Axis".

J Clin Endocrinol Metab
europepmc   +1 more source