Results 121 to 130 of about 948,845 (312)

Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson’s disease pathology

open access: yesJournal of Tissue Engineering
Growing evidence indicates that type 2 diabetes (T2D) is associated with an increased risk of developing Parkinson’s disease (PD) through shared disease mechanisms.
Alise Zagare   +14 more
doaj   +1 more source

Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance[S]

open access: yesJournal of Lipid Research, 2011
The mechanism of FFA-induced insulin resistance is not fully understood. We have searched for effector molecules(s) in FFA-induced insulin resistance. Palmitic acid (PA) but not oleic acid (OA) induced insulin resistance in L6 myotubes through C-Jun N ...
Myoung Sook Han   +13 more
doaj   +1 more source

Perbedaan Kadar Resistin Pada Obes Dengan Resistensi Insulin Dan Obes Tanpa Resistensi Insulin [PDF]

open access: yes, 2009
Resistin is an adipocytokine that secreted from adipose tissue, resistin level serum increased in obese patients. Resistin has important biological activity on glucose and lipid metabolism, and can affect insulin resistance. Previous study suggested that
Marfianti, E. (Erlina)
core  

Insulin Resistance [PDF]

open access: yesThe Journal of Pediatrics, 2012
Alan R, Sinaiko, Sonia, Caprio
openaire   +2 more sources

Insulin resistance in sepsis

open access: yesBritish Journal of Surgery, 2003
Basic understanding of the phenomenon remains ...
openaire   +2 more sources

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

open access: yesAdvanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa   +6 more
wiley   +1 more source

The Role of GABA and Insulin Regulated Aminopeptidase on Insulin Resistance and GLUT4 in Prediabetes and Type 2 Diabetes Mellitus

open access: yesمجله كليه طب الكندي
Background: Different proposed mechanisms for insulin resistance have been put forth to understand the relationship and changes in insulin resistance. Looking at the levels of insulin, the neurotransmitter gamma-aminobutyric acid, glucose transport type
Ismael Sadeq Khashan   +1 more
doaj   +1 more source

Role of obesity in development of insulin resistance: A review

open access: yesمجلة جامعة الزيتونة, 2022
The relationship between obesity and insulin resistance is widely accepted. This relationship represents several major health hazards including morbid obesity and insulin resistance complications worldwide.
Fathi Hudoud
doaj  

Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis. [PDF]

open access: yes, 2020
Fatty acid and triglyceride synthesis increases greatly in response to feeding and insulin. This lipogenic induction involves coordinate transcriptional activation of various enzymes in lipogenic pathway, including fatty acid synthase and glycerol-3 ...
Choi, Yoon   +4 more
core  

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

open access: yesAdvanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou   +5 more
wiley   +1 more source

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