Results 191 to 200 of about 861,807 (357)

HLA-DQA1*1 contributes to resistance and A1*3 confers susceptibility to Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects [PDF]

, 1991
Kazuya Yamagata, Toshiaki Hanafusa, Hideaki Nakajima, M. Sada, Hiroshi Amemiya, Tamio Noguchi, T Tanaka, Norio Kôno, S Tarui   +8 more
openalex   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Endoplasmic reticulum stress contributes to insulin resistance in Hashimoto's Thyroiditis. [PDF]

Endocr Connect
Zhou Q, Zhang LY, Gao XL, Zou CC, Liu H.
europepmc   +1 more source

Production of Inhibitor of Insulin-Receptor Tyrosine Kinase in Fibroblasts From Patient With Insulin Resistance and NIDDM [PDF]

, 1991
Paolo Sbraccia, Patricia A. Goodman, Betty A. Maddux, Kwok-Ying Wong, Y-D.I. Chen, Gerald M. Reaven, Ira D. Goldfine   +6 more
openalex   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

Atherosclerosis and Insulin Resistance: Is There a Link Between Them? [PDF]

Biomedicines
Brie AD, Christodorescu RM, Popescu R, Adam O, Tîrziu A, Brie DM.   +5 more
europepmc   +1 more source

Non-esterified fatty acids do not contribute to insulin resistance in persons at increased risk of developing Type 2 (non-insulin-dependent) diabetes mellitus [PDF]

, 1991
Johan G. Eriksson, Carola Saloranta, E. Wid�n, Agneta Ekstrand, A. Franssila-Kallunki, Camilla Schalin, Per‐Henrik Groop   +6 more
openalex   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Evaluating indices of insulin resistance and estimating the prevalence of insulin resistance in a large biobank cohort. [PDF]

Front Endocrinol (Lausanne)
Aliyu U, Toor SM, Abdalhakam I, Elrayess MA, Abou Samra AB, Albagha OME.   +5 more
europepmc   +1 more source

The association of the insulin resistance syndrome with impaired glucose tolerance and NIDDM in the Japanese general population: the Hisayama study [PDF]

, 1994
Akihiro Shinkawa, Yutaka Hasuo, M Fujishima, Takumi Ohmura, K. Ueda, Yutaka Kiyohara, Isao Kato, Hiroki Iwamoto, Kazuki Nakayama, K Nomiyama, Susumu Ohmori, Tadamasa Yoshitake   +11 more
openalex   +1 more source