Results 321 to 330 of about 543,808 (360)
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Neuroendocrine Control of Insulin Secretion
Diabetes, 1976The effects of thyrotropin-releasing hormone, luteinizing hormone-releasing hormone, substance P, somatostatin, and a partially purified hypothalamic extract on insulin secretion were tested both in vitro and in vivo. Only somatostatin and the hypothalamic extract affected insulin secretion.
R B, Lockhart-Ewart, C, Mok, J M, Martin
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Mechanisms of Insulin Secretion
New England Journal of Medicine, 1970IN the bodily economy of animals, including man, insulin has evolved into the premier regulator of storage and conservation of the three major foodstuffs.
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Multiscale Modeling of Insulin Secretion
IEEE Transactions on Biomedical Engineering, 2011Insulin secretion from pancreatic beta cells is a fundamental physiological process, and its impairment plays a pivotal role in the development of diabetes. Mathematical modeling of insulin secretion has a long history, both on the level of the entire body and on the cellular and subcellular scale.
PEDERSEN, MORTEN GRAM +2 more
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Desensitization of insulin secretion
Biochemical Pharmacology, 2002Desensitization of insulin secretion describes a reversible state of decreased secretory responsiveness of the pancreatic beta-cell, induced by a prolonged exposure to a multitude of stimuli. These include the main physiological stimulator, glucose, but also other nutrients like free fatty acids and practically all pharmacological stimulators acting by
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Metabolism, 1984
Recent advances in insulin secretion indicate that pertussis toxin abolishes the inhibition by alpha 2 adrenoceptor activation of insulin release by the pancreas. Pertussis toxin adenosine diphosphate (ADP) ribosylates an inhibitory guanine nucleotide-binding protein (Ni) involved in inhibition of adenylate cyclase.
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Recent advances in insulin secretion indicate that pertussis toxin abolishes the inhibition by alpha 2 adrenoceptor activation of insulin release by the pancreas. Pertussis toxin adenosine diphosphate (ADP) ribosylates an inhibitory guanine nucleotide-binding protein (Ni) involved in inhibition of adenylate cyclase.
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Mechanisms controlling pancreatic islet cell function in insulin secretion
Nature Reviews Molecular Cell Biology, 2021Jonathan Campbell, Christopher B Newgard
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[Insulin secretion and insulin resistance].
Nihon rinsho. Japanese journal of clinical medicine, 2014Aging is a critical risk factor for impaired glucose tolerance and diabetes. In Japan, 8.9 million people are reported to have diabetes, and 37% of those are over the age of 70. In this review, we summarize the current evidence on how aging affects pancreatic beta cell function, beta cell mass, insulin secretion and insulin sensitivity.
Yasuharu, Ohta, Yukio, Tanizawa
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Insulin Inhibition of Insulin Secretion
New England Journal of Medicine, 1982openaire +2 more sources
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion
Cell Metabolism, 2021Guo-Fang Zhang +2 more
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