Nardilysin in adipocyte regulates insulin sensitivity via HIF1α and PPARγ. [PDF]
Matsuda S +9 more
europepmc +1 more source
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen +15 more
wiley +1 more source
Extracellular vesicles carrying surface-anchored adiponectin prevent obesity-related metabolic complications by enhancing insulin sensitivity. [PDF]
Blandin A +20 more
europepmc +1 more source
Exercise induced hypoglycaemia in type 1 diabetic patients:canit be prevented?
GEAT M. +2 more
core
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu +10 more
wiley +1 more source
Disentangling metabolic impairment in the liver-heart axis: tissue-specific insulin sensitivity in type 2 diabetes. [PDF]
Martín-Saladich Q +6 more
europepmc +1 more source
Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim +7 more
wiley +1 more source
Insulin sensitivity in individuals with burnout is associated with physical activity level - a study using oral glucose tolerance test. [PDF]
Lennartsson AK +3 more
europepmc +1 more source
Resistance training combined with ursolic acid supplementation restores anabolic signaling (PI3K/mTORC1) suppressed by diabetes, helping preserve muscle mass. This strategy may offer a potential therapeutic approach to combat muscle atrophy and support healthy aging in diabetic conditions.
Ashkan Sadeghi +4 more
wiley +1 more source
Negative correlation between microRNA and insulin sensitivity gene expression in adipose tissue: potential implications for diabetes and neurodegenerative diseases. [PDF]
Podraza J +10 more
europepmc +1 more source

