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New Insulins and Insulin Therapy [PDF]
Diabetes Technology & Therapeutics, 2013 The introduction of the so-called 'designer' insulins, the insulin analogues, has offered new opportunities in the clinical management of diabetes. Two additional new entities are close to reaching clinical practice. Linjeta™ (formally called VIAject) is not an analogue but rather a different formulation of human insulin which may give it a more rapid ...
Bolinder, Jan +2 more
openaire +7 more sources
The future of insulin therapy [PDF]
Diabetes Research and Clinical Practice, 2021 Although insulin therapy was already introduced one-hundred years ago, insulin formulations are still being refined to reduce the risk of hypoglycaemia and of other insulin side effects such as weight gain. This review summarises the available clinical data for some ongoing developments of new insulins and evaluates their potential for future insulin ...
openaire +2 more sources
Insulin Analogues for Insulin Receptor Studies and Medical Applications [PDF]
, 2012 The structure of insulin molecule was determined by Dorothy Hodgkin in 1969. Subsequently, it has been established that insulin must rearrange upon binding to its receptor (Insulin Receptor – IR).
Watson, Christopher John
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New Insulins, Biosimilars, and Insulin Therapy [PDF]
Diabetes Technology & Therapeutics, 2016 Exogenous insulin has greatly changed the outlook for patients with diabetes ever since its discovery and isolation. Yet, serious complications can result as patients experience both hyperglycemic and hypoglycemic states, even when they strictly follow an insulin regimen. Several chemically or genetically modified insulins have been developed that tune
Thomas, Danne +2 more
openaire +11 more sources
Management and efficacy of intensified insulin therapy starting in outpatients [PDF]
, 1989 Diabetic patients under multiple injection insulin therapy (i.e., intensified insulin therapy, IIT) usually start this treatment during hospitalization. We report here on the logistics, efficacy, and safety of IIT, started in outpatients.
Winkelmann, W. +11 more
core +1 more source
Blood Glucose Meter Buying Behavior of Diabetic Patients: Factors Influencing Purchase
Frontiers in Public Health, 2022 ObjectiveTo understand the blood glucose meter buying behavior of type 2 diabetic patients with poor glycemic control (two or more HbA1c ≥ 8% during visits in one year) and identify factors influencing it.MethodsA survey was conducted among 585 diabetic ...
Bai-ling Pan +3 more
doaj +1 more source
Challenges and unmet needs in basal insulin therapy: lessons from the Asian experience [PDF]
, 2017 Basal insulin therapy can improve glycemic control in people with type 2 diabetes. However, timely initiation, optimal titration, and proper adherence to prescribed basal insulin regimens are necessary to achieve optimal glycemic control.
Sony Wibisono Mudjanarko +10 more
core +2 more sources
Clinical and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes [PDF]
, 2004 Objectives: To assess the clinical and cost-effectiveness of continuous subcutaneous insulin infusion (CSII) compared with multiple daily injections (MDI) in the delivery of intensive insulin therapy for the treatment of diabetes mellitus.
Green, C. +9 more
core +1 more source
Data on insulin therapy refusal among type II diabetes mellitus patients in Mashhad, Iran
Data in Brief, 2018 Insulin has been considered as a therapy option of last resort in type 2 diabetes (T2DM) management. Delay in insulin therapy is common in these patients.
Zahra Mostafavian +4 more
doaj +1 more source
Adding pioglitazone to insulin containing regimens in type 2 diabetes : systematic review and meta-analysis [PDF]
, 2009 Background Type 2 diabetes is treated in a stepwise manner, progressing from diet and physical activity to oral antidiabetic agents and insulin. The oral agent pioglitazone is licensed for use with insulin when metformin is contraindicated or not ...
Waugh Norman +8 more
core +1 more source