Results 21 to 30 of about 445,193 (314)

Adding pioglitazone to insulin containing regimens in type 2 diabetes : systematic review and meta-analysis [PDF]

, 2009
Background Type 2 diabetes is treated in a stepwise manner, progressing from diet and physical activity to oral antidiabetic agents and insulin. The oral agent pioglitazone is licensed for use with insulin when metformin is contraindicated or not ...
Waugh Norman, Christine Clar, Clar Christine, Waugh, Norman, Norman Waugh, Royle Pamela, Clar, C., Royle, Pamela, Pamela Royle   +8 more
core   +1 more source

Capacity and confidence building for general practitioners on optimum insulin use

Journal of Family Medicine and Primary Care, 2019
Type 2 diabetes is characterised by a progressive decline in insulin secretion, and sooner or later patients require insulin therapy. However, physicians are reluctant to initiate insulin therapy because of perceived inadequacy in managing insulin ...
Sanjay Kalra, Prasun Deb, Kalyan K Gangopadhyay, Sunil Gupta, Abhay Ahluwalia   +4 more
doaj   +1 more source

Molecular mechanisms of insulin resistance in chronic liver disease [PDF]

, 2008
The work presented here analyses the role of PP2A in the dysregulation of glucose metabolism in the setting of chronic hepatitis C. We propose a new model for virus induced insulin resistance development through the overexpression of PP2A in the liver ...
Bernsmeier, Christine
core   +1 more source

Decision-making: initiating insulin therapy for adults with diabetes [PDF]

, 2009
<b>AIM:</b> This paper is a report of a study to describe nurses' perceptions of decision-making and the evidence base for the initiation of insulin therapy.
Dromgoole, P., Thompson, K., Brown, F., Lowes, L., McDowell, J., Joan R.S. McDowell, Paul Dromgoole, Kate Thompson, Eileen V. Turner, Vivien Coates, Florence Brown, Lesley Lowes, Coates, V., Turner, E.V., Ruth Davis   +14 more
core   +1 more source

Secondary failure of oral therapy in patients with type 2 diabetes: How to overcome it? [PDF]

Scripta Medica
Background/Aim: Secondary failure of oral therapy occurs after a long period of successful use of oral antidiabetic drugs. The exact mechanism of its occurrence is not known.
Marković Aleksandra, Dojčinović Tamara, Risović Ivona, Grujičić Milorad, Malinović-Pančić Jelena   +4 more
doaj   +1 more source

Cystic Fibrosis - Related Diabetes

Journal of Education, Health and Sport, 2021
Cystic fibrosis (CF) is life-shortening autosomal recessive disease, caused by mutations in the cystic fibrosis transmembrane conductance regulator protein. The most common of CF complications is cystic fibrosis-related diabetes (CFRD).
Marcin Makuch, Marcelina Makuch
doaj   +1 more source

Strategies to optimize glucose control during exercise in subjects with type 1 diabetes [PDF]

CellR4, 2020
Regular physical activity is highly recommended in subjects with type 1 diabetes (T1D) because of its beneficial impact on body composition, cardiovascular disease risk profile, glucose control and psychological wellbeing.
F. Silvestri, F. Costantino, V. Tromba
doaj   +1 more source

The effects of metformin in type 1 diabetes mellitus

BMC Endocrine Disorders, 2018
Background This retrospective study investigated the effect of adding metformin to pharmacologic insulin dosing in type 1 diabetics on insulin therapy 1 year after treatment compared with patients on insulin therapy alone. Methods Twenty-nine adults with
Selvihan Beysel, Ilknur Ozturk Unsal, Muhammed Kizilgul, Mustafa Caliskan, Bekir Ucan, Erman Cakal   +5 more
doaj   +1 more source

Insulin Therapy and Cancer [PDF]

Diabetes Care, 2013
That diabetes is associated with an increased lifetime risk of developing malignancy is now well established (1,2). For some specific malignancies, explanation of that increased risk is possible, though usually unproven. For example, the marked increase in pancreatic cancer incidence in type 2 diabetes may or may not be due to misattribution of type of
openaire   +3 more sources

Gestational diabetes mellitus: A Narrative Review

Medical Journal of Babylon, 2021
Diabetes mellitus (DM) is a chronic disease that needs medical support and continuing patient education to avoid acute complications and decrease the long-term complications. The prevalence of diabetes is high in many areas, especially Asian.
Alaa Ibrahim Ali, Wassan Nori
doaj   +1 more source