Results 21 to 30 of about 3,155,278 (304)

High-Fat Diet : Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse [PDF]

, 2010
Background: Obesity induced by high fat (HF) diet is associated with inflammation which contributes to development of insulin resistance. Most prior studies have focused on adipose tissue as the source of obesity-associated inflammation.
Ding, Shengli, Magness, Scott, Scull, Brooks P., Jobin, Christian, Schwerbrock, Nicole M. J., Lund, Pauline K., Chi, Michael M., Rigby, Rachael   +7 more
core   +6 more sources

Capacity and confidence building for general practitioners on optimum insulin use

Journal of Family Medicine and Primary Care, 2019
Type 2 diabetes is characterised by a progressive decline in insulin secretion, and sooner or later patients require insulin therapy. However, physicians are reluctant to initiate insulin therapy because of perceived inadequacy in managing insulin ...
Sanjay Kalra, Prasun Deb, Kalyan K Gangopadhyay, Sunil Gupta, Abhay Ahluwalia   +4 more
doaj   +1 more source

Molecular mechanisms of insulin resistance in chronic liver disease [PDF]

, 2008
The work presented here analyses the role of PP2A in the dysregulation of glucose metabolism in the setting of chronic hepatitis C. We propose a new model for virus induced insulin resistance development through the overexpression of PP2A in the liver ...
Bernsmeier, Christine
core   +1 more source

The evolution of insulin therapy [PDF]

Diabetes Research and Clinical Practice, 2021
Evolution in medicine is generally driven by clinical need, hand in hand with opportunities generated by novel chemical and mechanical engineering technologies. Since 1921 that has been a continuing paradigm for insulin therapy, some advances being a continual process, and others arising from external scientific or engineering developments ...
openaire   +3 more sources

Decision-making: initiating insulin therapy for adults with diabetes [PDF]

, 2009
<b>AIM:</b> This paper is a report of a study to describe nurses' perceptions of decision-making and the evidence base for the initiation of insulin therapy.
Dromgoole, P., Thompson, K., Brown, F., Lowes, L., McDowell, J., Joan R.S. McDowell, Paul Dromgoole, Kate Thompson, Eileen V. Turner, Vivien Coates, Florence Brown, Lesley Lowes, Coates, V., Turner, E.V., Ruth Davis, Brown, Florence, Davis, Ruth Hannah, McDowell, Joan R.S., Turner, Eileen V., Dromgoole, Paul, Coates, Vivien, Lowes, Lesley Madeline, Thompson, Kate   +22 more
core   +1 more source

Secondary failure of oral therapy in patients with type 2 diabetes: How to overcome it? [PDF]

Scripta Medica
Background/Aim: Secondary failure of oral therapy occurs after a long period of successful use of oral antidiabetic drugs. The exact mechanism of its occurrence is not known.
Marković Aleksandra, Dojčinović Tamara, Risović Ivona, Grujičić Milorad, Malinović-Pančić Jelena   +4 more
doaj   +1 more source

Adherence to Insulin Therapy [PDF]

Diabetes Spectrum, 2016
IN BRIEF Six million people with diabetes use insulin either alone or in combination with an oral medication. Many barriers exist that lead to poor adherence with insulin. However, there is an underwhelming amount of data on interventions to address these barriers and improve insulin adherence.
Sarbacker, G. Blair, Urteaga, Elizabeth M.   +1 more
openaire   +2 more sources

The effects of metformin in type 1 diabetes mellitus

BMC Endocrine Disorders, 2018
Background This retrospective study investigated the effect of adding metformin to pharmacologic insulin dosing in type 1 diabetics on insulin therapy 1 year after treatment compared with patients on insulin therapy alone. Methods Twenty-nine adults with
Selvihan Beysel, Ilknur Ozturk Unsal, Muhammed Kizilgul, Mustafa Caliskan, Bekir Ucan, Erman Cakal   +5 more
doaj   +1 more source

Cystic Fibrosis - Related Diabetes

Journal of Education, Health and Sport, 2021
Cystic fibrosis (CF) is life-shortening autosomal recessive disease, caused by mutations in the cystic fibrosis transmembrane conductance regulator protein. The most common of CF complications is cystic fibrosis-related diabetes (CFRD).
Marcin Makuch, Marcelina Makuch
doaj   +1 more source

Strategies to optimize glucose control during exercise in subjects with type 1 diabetes [PDF]

CellR4, 2020
Regular physical activity is highly recommended in subjects with type 1 diabetes (T1D) because of its beneficial impact on body composition, cardiovascular disease risk profile, glucose control and psychological wellbeing.
F. Silvestri, F. Costantino, V. Tromba
doaj   +1 more source