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Insulinoma

Current Treatment Options in Oncology, 2003
Insulinomas are the most common islet cell tumors and are located almost exclusively in the pancreas. Most of these tumors are sporadic, but they may also be associated with the multiple endocrine neoplasia type I syndrome. More than 90% of insulinomas are benign. Preoperative radiographic localization may prove difficult.
Alan P.B. Dackiw, Andrew R. Burns
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Insulinoma

Current Opinion in Endocrinology & Diabetes, 2000
Insulinoma is the most common pancreatic islet cell tumor, usually presenting with symptoms of neuroglycopenia. Diagnosis depends on a high index of suspicion, together with the demonstration of endogenous hyperinsulinemic hypoglycemia. Although the requirement for preoperative localization is controversial, the minimally invasive but highly sensitive ...
Tso, AWK, Lam, KSL
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Insulinoma

Neuroendocrinology, 2004
More than 90% of insulinomas are benign tumors. Insulinomas cause hypoglycemia and thereby symptoms of neuroglycopenia and catecholamine response. During symptoms, blood glucose levels should be less than 40 mg/dl (less than 2.2 mmol/l), concomitant insulin levels should be ≧6 IU/ml (≧43 pmol/l) and concomitant C-peptide levels ≧0.2 pmol/l.
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Insulinoma in Pregnancy

Experimental and Clinical Endocrinology & Diabetes, 2009
Insulinomas are rare, mostly benign neuroendocrine tumours with an incidence of approximately four cases per million person per year. Only isolated case reports of insulinomas occurring in pregnancy have been documented. Clinical signs and symptoms of insulinoma appear to be attenuated and, in some cases, even masked by pregnancy.
B Besemer, K Müssig
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Insulinoma

Baillière's Clinical Gastroenterology, 1996
Symptoms most characteristically diagnostic of insulinoma are those of neuroglycopenia. The combination of hypoglycemia and endogenous hyperinsulinemia are pathognomonic of insulinoma. Several localization techniques are available, the choice of which best depends on the best expertise at individual institutions.
openaire   +5 more sources

Streptozotocin for Insulinoma

Annals of Internal Medicine, 1971
Excerpt To the editor: Schriebman, Goransky De Koliren, and Arky (Ann Intern Med74:399-403, 1971) reported on a patient with metastatic insulinoma who had been treated with streptozotocin.
Edit Piroska, Eva Kollin
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INSULINOMA IN THE DOG

Australian Veterinary Journal, 1980
SUMMARY Four clinical cases of insulinoma in the dog are described. In each, nervous signs increased in frequency and severity over a period of approximately 4 months. Diagnosis was made on clinical signs, blood glucose concentration, response to glucose therapy and, in the 2 cases in which an radioimmunoassay was performed, blood insulin levels ...
C. W. Prescott, H Thompson
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LOCALISATION OF INSULINOMAS

The Lancet, 1978
Small insulinomas may be undetectable by arteriography or palpation of the pancreas. They can be identified, however, by the point at which high insulin levels are detected in the venous effluent sampled at several sites by catheterisation of the splenic and portal veins at laparotomy or via the percutaneous transhepatic route.
E.C.G. Lee   +4 more
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Insulinoma in a cat

Journal of Small Animal Practice, 2007
A 14‐year‐old domestic shorthair cat was presented with hypoglycaemia and seizures of several weeks duration. Bloodwork revealed hypoglycaemia (1·83 mmol/l; reference range 4·22‐8·05 mmol/l) with concurrent normal insulin levels (171 pmol/l; reference range 72‐583 pmol/l).
R. M Bright, S. N Greene
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