Results 81 to 90 of about 2,408,532 (316)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Improving access to chronic pain care with central referral and triage: The 6-year findings from a single-entry model

Canadian Journal of Pain
Background Despite the established efficacy of multidisciplinary chronic pain care, barriers such as inflated referral wait times and uncoordinated care further hinder patient health care access.Aims Here we describe the evolution of a single-entry model
Tania Di Renna, Emeralda Burke, Anuj Bhatia, Hance Clarke, David Flamer, John Flannery, Andrea Furlan, Dinesh Kumbhare, James Khan, Karim Ladha, Howard Meng, Andrew Smith, David Sussman, Rachael Bosma   +13 more
doaj   +1 more source

Efeitos da enramicina e da monensina sódica no consumo de matéria seca, na fermentação ruminal e no comportamento alimentar em bovinos alimentados com dietas com alto nível de concentrado Effects of enramycin and sodium monensin on dry matter intake, ruminal fermentation and alimentary behavior in bovine fed high-concentrate diets

Revista Brasileira de Zootecnia, 2008
Estudaram-se os efeitos da administração de enramicina e monensina sódica no consumo de matéria seca (MS), na fermentação ruminal e no comportamento alimentar de bovinos.
Luiz Felipe de Onofre Borges, Roberta Passini, Paula Marques Meyer, Alexandre Vaz Pires, Paulo Henrique Mazza Rodrigues   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Effects of cutting height and bacterial inoculant on corn silage aerobic stability and nutrient digestibility by sheep

Revista Brasileira de Zootecnia, 2020
In this study, we aimed to determine the effects of cutting height (25 or 40 cm above ground) and bacterial inoculation (a combined inoculant of Lactobacillus plantarum and Propionibacterium acidipropionici) on the chemical and microbial compositions ...
Rita de Cássia Almeida de Mendonça, Marcus Vinicius Santa Brígida Cardoso, Sarah Oliveira Sousa Pantoja, Melany Simões de Souza, Felipe Nogueira Domingues, Cristian Faturi, Thiago Carvalho da Silva, Aníbal Coutinho do Rêgo   +7 more
doaj   +1 more source

A Role for Peripheral Anandamide and 2-Arachidonoylglycerol in Short-Term Food Intake and Orexigenic Hypothalamic Responses in a Species with Continuous Nutrient Delivery [PDF]

, 2021
Isabel van Ackern, Angela Kuhla, Björn Kuhla   +2 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Associations of Adiponectin with Adiposity, Insulin Sensitivity, and Diet in Young, Healthy, Mexican Americans and Non-Latino White Adults. [PDF]

, 2015
Low circulating adiponectin levels may contribute to higher diabetes risk among Mexican Americans (MA) compared to non-Latino whites (NLW). Our objective was to determine if among young healthy adult MAs have lower adiponectin than NLWs, independent of ...
Bessesen, Daniel H, Havranek, Edward P, Long, Carlin S, Low Wang, Cecilia C, Pereira, Rocio I, Wolfe, Pamela   +5 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Avaliação do consumo e de metabólitos plasmáticos de cabras gestantes com duas condições corporais alimentadas com dietas formuladas com diferentes níveis de energia Effects of body condition score and dietary energy levels on performance of pregnant dairy goats

Revista Brasileira de Zootecnia, 2007
Este estudo foi conduzido com o objetivo de avaliar as relações entre as diferentes condições corporais e os níveis de energia nas dietas sobre o consumo, a variação de peso e a concentração de ácidos graxos não-esterificados (AGNE) no plasma de cabras ...
Carla Aparecida Florentino Rodrigues, Marcelo Teixeira Rodrigues, Renata Helena Branco, Giovanni Ribeiro de Carvalho, Robledo de Almeida Torres, Rodolpho de Almeida Torres Filho   +5 more
doaj   +1 more source