Results 51 to 60 of about 2,117 (310)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

A note on the S-matrix bootstrap for the 2d O(N) bosonic model

Journal of High Energy Physics, 2018
In this work we apply the S-matrix bootstrap maximization program to the 2d bosonic O(N) integrable model which has N species of scalar particles of mass m and no bound states.
Yifei He, Andrew Irrgang, Martin Kruczenski   +2 more
doaj   +1 more source

Alternate approach to no integrability field theory

Mathematical and Computer Modelling, 1989
This is another paper in a series which illustrates that foregoing the rules of traditional calculus opens up a realm of possibilities. We study the ''aesthetic field theory'', although the techniques are more general. We introduce a new integration procedure which is consistent with aesthetic principles.
openaire   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Higher Time-Derivative Theories from Space–Time Interchanged Integrable Field Theories

Universe
We compare a relativistic and a nonrelativistic version of Ostrogradsky’s method for higher-time derivative theories extended to scalar field theories and consider as an alternative a multi-field variant.
Andreas Fring, Takano Taira, Bethan Turner   +2 more
doaj   +1 more source

T T ¯ $$ T\overline{T} $$ deformations and the width of fundamental particles

Journal of High Energy Physics, 2022
We provide a simple geometric meaning for deformations of so-called T T ¯ $$ T\overline{T} $$ type in relativistic and non-relativistic systems. Deformations by the cross products of energy and momentum currents in integrable quantum field theories are ...
John Cardy, Benjamin Doyon
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Integrable coupled bosonic massive Thirring model and its nonlocal reductions

Journal of High Energy Physics
A coupled bosonic massive Thirring model (BMTM), involving an interaction between the two independent spinors, is introduced and shown to be integrable.
B. Basu-Mallick, Debdeep Sinha
doaj   +1 more source

On the hydrodynamics of unstable excitations

Journal of High Energy Physics, 2020
The generalized hydrodynamic (GHD) approach has been extremely successful in describing the out-of-equilibrium properties of a great variety of integrable many-body quantum systems.
Olalla A. Castro-Alvaredo, Cecilia De Fazio, Benjamin Doyon, Francesco Ravanini   +3 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source