Results 81 to 90 of about 358,156 (289)
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
A class of multidimensional integrable hierarchies and their reductions [PDF]
Theoretical and Mathematical Physics, 2009 A class of multidimensional integrable hierarchies connected with commutation of general (unreduced) (N+1)-dimensional vector fields containing derivative over spectral variable is considered. They are represented in the form of generating equation, as well as in the Lax-Sato form.
openaire +3 more sources
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
On Classification of Integrable Davey-Stewartson Type Equations [PDF]
, 2013 This paper is devoted to the classification of integrable Davey-Stewartson type equations. A list of potentially deformable dispersionless systems is obtained through the requirement that such systems must be generated by a polynomial dispersionless Lax ...
Novikov, Vladimir, Huard, Benoit
core +1 more source
Two Expanding Integrable Models of the Geng-Cao Hierarchy
Abstract and Applied Analysis, 2014 As far as linear integrable couplings are concerned, one has obtained some rich and interesting results. In the paper, we will deduce two kinds of expanding integrable models of the Geng-Cao (GC) hierarchy by constructing different 6-dimensional Lie ...
Xiurong Guo, Yufeng Zhang, Xuping Zhang
doaj +1 more source
Analytic-bilinear approach to integrable hierarchies. I. Generalized KP hierarchy [PDF]
Journal of Mathematical Physics, 1998 An analytic-bilinear approach for construction and study of integrable hierarchies, in particular, the KP hierarchy is proposed. It starts with the generalized Hirota identity for the Cauchy–Baker–Akhiezer (CBA) function and leads to a generalized KP hierarchy in the form of compact functional equations containing a special shift operator.
BOGDANOV L. V., KONOPELCHENKO, Boris
openaire +4 more sources
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Integrable discretization of recursion operators and unified bilinear forms to soliton hierarchies [PDF]
Open Communications in Nonlinear Mathematical PhysicsIn this paper, we give a procedure for discretizing recursion operators by utilizing unified bilinear forms within integrable hierarchies. To illustrate this approach, we present unified bilinear forms for both the AKNS hierarchy and the KdV hierarchy ...
Xingbiao Hu, Guofu Yu, Yingnan Zhang
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source