Results 71 to 80 of about 661 (265)
A class of multidimensional integrable hierarchies and their reductions [PDF]
Theoretical and Mathematical Physics, 2009 A class of multidimensional integrable hierarchies connected with commutation of general (unreduced) (N+1)-dimensional vector fields containing derivative over spectral variable is considered. They are represented in the form of generating equation, as well as in the Lax-Sato form.
openaire +3 more sources
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Integrable discretization of recursion operators and unified bilinear forms to soliton hierarchies [PDF]
Open Communications in Nonlinear Mathematical PhysicsIn this paper, we give a procedure for discretizing recursion operators by utilizing unified bilinear forms within integrable hierarchies. To illustrate this approach, we present unified bilinear forms for both the AKNS hierarchy and the KdV hierarchy ...
Xingbiao Hu, Guofu Yu, Yingnan Zhang
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Abstract and Applied Analysis, 2014 Based on zero curvature equations from semidirect sums of Lie algebras, we construct tri-integrable couplings of the Giachetti-Johnson (GJ) hierarchy of soliton equations and establish Hamiltonian structures of the resulting tri-integrable couplings by ...
Lei Wang, Ya-Ning Tang
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Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley +1 more source
Journal of High Energy Physics, 2019 We present a new set of boundary conditions for General Relativity on AdS3, where the dynamics of the boundary degrees of freedom are described by two independent left and right members of the Gardner hierarchy of integrable equations, also known as the “
Emilio Ojeda, Alfredo Pérez
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New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source