THE INFLUENCE OF LIFE EXPECTANCY IN THE DETERMINATION OF PENSION FUND INVESTMENTS [PDF]
Preparating one’s retirement is important for many people, because an employee will often have no salary anymore after retiring, but his/her daily needs are still remained.
Kristiani, Farah
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
ANALISIS MODEL PROBABILISTIK PUNAHNYA MUTAN PARASIT MALARIA YANG RESISTEN TERHADAP KLOROKUIN PLUS AMODIAKUIN [PDF]
In this paper probabilistic models are developed from a model of malaria parasite population dynamics proposed by Macdonald [1] based on Galton-Watson branching and generating Negative Binomial distribution with maximum likelihood estimation, to test a ...
Nainggolan, Jonner
core
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Lorentzian path integral for quantum tunneling and WKB approximation for wave-function
Recently, the Lorentzian path integral formulation using the Picard–Lefschetz theory has attracted much attention in quantum cosmology. In this paper, we analyze the tunneling amplitude in quantum mechanics by using the Lorentzian Picard–Lefschetz ...
Hiroki Matsui
doaj +1 more source
Constraint Design Rewriting [PDF]
We propose an algebraic approach to the design and transformation of constraint networks, inspired by Architectural Design Rewriting. The approach can be understood as (i) an extension of ADR with constraints, and (ii) an application of ADR to the design
Lluch-Lafuente, Alberto +2 more
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Household behavior change for climate change response: an integral scan [PDF]
The question of how to successfully facilitate the changes needed to avoid dangerous climate change has become a critical one for researchers and practitioners.
Riedy, C
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Mixing Visual and Textual Constraint Languages [PDF]
The Object Constraint Language (OCL) is a precise language for notating behavioural constraints on UML models. Constraint diagrams have been proposed as a means of notating similar constraints, but in a visual form.
Howse, John +3 more
core +1 more source

