Results 61 to 70 of about 1,573,513 (300)
View Constraints: an Interpretation of Integrity Constraints for Security [PDF]
, 1997 Security is seen as fondamental to S.W.I.F.T.'s business, second only to network availability. The security infrastructure in terms of organisation, direction, processes and tools, must be appropriate. The world as we know it is changing rapidly as technology marches forward and as the modern business world expands to take advantage of the new ...
openaire +4 more sources
Household behavior change for climate change response: an integral scan [PDF]
, 2009 The question of how to successfully facilitate the changes needed to avoid dangerous climate change has become a critical one for researchers and practitioners.
Riedy, C
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Timetabling in constraint logic programming [PDF]
, 1996 In this paper we describe the timetabling problem and its solvability in a Constraint Logic Programming Language. A solution to the problem has been developed and implemented in ECLiPSe, since it deals with finite domains, it has well-defined ...
Kambi, M, Gilbert, D
core +3 more sources
Lorentzian path integral for quantum tunneling and WKB approximation for wave-function
European Physical Journal C: Particles and Fields, 2022 Recently, the Lorentzian path integral formulation using the Picard–Lefschetz theory has attracted much attention in quantum cosmology. In this paper, we analyze the tunneling amplitude in quantum mechanics by using the Lorentzian Picard–Lefschetz ...
Hiroki Matsui
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Optimal periodic control for scalar dynamics under integral constraint on the input
, 2020 International audienceThis paper studies a periodic optimal control problem governed by a one-dimensional system, linear with respect to the control u, under an integral constraint on u.
Tani, Fatima Zahra +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source