Results 81 to 90 of about 1,573,513 (300)

Integrating Algorithms for Integrable Affine Constraints

open access: yesIEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences, 2011
This letter presents integrating algorithms for affine constraints defined on a manifold. We first explain definition and geometric representation of affine constraints. Next, we derive integrating algorithms to calculate independent first integrals of affine constraints for the two cases where the they are completely integrable and partially ...
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Symmetry properties of a generalized Korteweg-de Vries equation and some explicit solutions

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2005
The symmetry group method is applied to a generalized Korteweg-de Vries equation and several classes of group invariant solutions for it are obtained by means of this technique. Polynomial, trigonometric, and elliptic function solutions can be calculated.
Paul Bracken
doaj   +1 more source

Short and long supports for constraint propagation [PDF]

open access: yes, 2013
Special-purpose constraint propagation algorithms frequently make implicit use of short supports -- by examining a subset of the variables, they can infer support (a justification that a variable-value pair may still form part of an assignment that ...
Gent, Ian Philip   +5 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

On the relation between operator constraint, master constraint, reduced phase space and path integral quantization

open access: yes, 2010
International audiencePath integral formulations for gauge theories must start from the canonical formulation in order to obtain the correct measure. A possible avenue to derive it is to start from the reduced phase space formulation.
T Thiemann   +5 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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