Results 81 to 90 of about 1,512,981 (300)

Integrating Algorithms for Integrable Affine Constraints

IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences, 2011
This letter presents integrating algorithms for affine constraints defined on a manifold. We first explain definition and geometric representation of affine constraints. Next, we derive integrating algorithms to calculate independent first integrals of affine constraints for the two cases where the they are completely integrable and partially ...
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Short and long supports for constraint propagation [PDF]

, 2013
Special-purpose constraint propagation algorithms frequently make implicit use of short supports -- by examining a subset of the variables, they can infer support (a justification that a variable-value pair may still form part of an assignment that ...
Gent, Ian Philip, Miguel, Ian James, Jefferson, Christopher Anthony, Nightingale, Peter   +3 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Symmetry properties of a generalized Korteweg-de Vries equation and some explicit solutions

International Journal of Mathematics and Mathematical Sciences, 2005
The symmetry group method is applied to a generalized Korteweg-de Vries equation and several classes of group invariant solutions for it are obtained by means of this technique. Polynomial, trigonometric, and elliptic function solutions can be calculated.
Paul Bracken
doaj   +1 more source

Dominion : an architecture-driven approach to generating efficient constraint solvers [PDF]

, 2011
This work is supported by the EPSRC grant “A Constraint Solver Synthesiser” (EP/H004092/1) and SICSA studentships.Constraints are used to solve combinatorial problems in a variety of industrial and academic disciplines.
Balasubramaniam, Dharini, Chris Jefferson, De Silva, Lakshitha Ramesh, Peter Nightingale, Dharini Balasubramaniam, Miguel, Ian James, Jefferson, Christopher Anthony, Lakshitha de Silva, Kotthoff, Lars, Nightingale, Peter, Ian Miguel, Lars Kotthoff   +11 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Constraint Diagrams: A Step Beyond UML [PDF]

, 1999
The Unified Modeling Language (UML) is a set of notations for modelling object-oriented systems. It has become the de facto standard. Most of its notations are diagrammatic.
Howse, John, Gil, Joseph, Kent, Stuart
core   +1 more source