Results 81 to 90 of about 502,946 (294)

Integral constraints in multiple scales problems with a slowly varying microstructure

European Journal of Applied Mathematics
Asymptotic homogenisation is considered for problems with integral constraints imposed on a slowly varying microstructure; an insulator with an array of perfectly dielectric inclusions of slowly varying size serves as a paradigm.
Amy Kent, Sarah L. Waters, James M. Oliver, Stephen Jonathan Chapman   +3 more
doaj   +1 more source

Generalization of Agranovich-Toshich transformation and constraint free bosonic representation for systems of truncated oscillators

, 1995
The generalization of Agranovich-Toshich representation of paulion operators in terms of bosonic ones for the case of truncated oscillators of higher ranks is represented.
A V Ilinskaia, Agranovich V M, Fradkin E, Ilinskaya A V, K N Ilinski   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

H∞ Optimal Performance Design of an Unstable Plant under Bode Integral Constraint

Complexity, 2018
This paper proposed the H∞ state feedback and H∞ output feedback design methods for unstable plants, which improved the original H∞ state feedback and H∞ output feedback.
Fanwei Meng, Aiping Pang, Xuefei Dong, Chang Han, Xiaopeng Sha   +4 more
doaj   +1 more source

Falling of a viscous jet onto a moving surface [PDF]

, 2006
We analyze the stationary flow of a jet of Newtonian fluid that is drawn by gravity onto a moving surface. The situation is modeled by a third-order ODE on a domain of unknown length and with an additional integral condition; by solving part of the ...
Aarts, A. C. T., Hlod, A., Peletier, M. A., Van De Ven, A. A. F.   +3 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The Kantorovich Inequality under Integral Constraints

Journal of Mathematical Analysis and Applications, 1994
Let \(f: [0,1]\to [m,M]\), where \(0< m ...
MIGLIACCIO, LUCIA, L. Nania
openaire   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source