Results 71 to 80 of about 157,958 (265)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Revista Brasileira de Educação do CampoInclusive education is a right guaranteed to all in Brazil, and teacher training from the perspective of integral education seeks the comprehensive and multidimensional development of people. So, based on the research question: what knowledge in the area
Fernanda Matrigani Mercado Gutierres de Queiroz +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
SENSE OF LIFE´S DEVELOPMENT IN HIGHER EDUCATION STUDENTS: A HUMANIST APPROACH
Ra Ximhai, 2018 The following work was made with the intention of contributing to the essential formation of Higher Education students. The objective of this study was to promote the development of the sense of life in the students of the Technological Institute of Los ...
Gloria Patiño-Armenta +3 more
doaj
Engineering Education in an Integrated Setting
International Journal of Engineering Pedagogy (iJEP), 2018 This paper serves to give brief overviews of key issues in five case studies in engineering technology stand-alone project based courses within a standard scholastic framework. The courses were offered in a range of scenarios with significant international student participation.
Richard Wood +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
INTEGRAL EDUCATION: SUBJECTIVE PUBLIC RIGHT
Educação: Teoria e Prática, 2018 The idea of integral education involves multiple possibilities of comprehension, particularly in policies, programs, projects, among other aspects of the organization of educational space, related to the expansion of the time that students spent in ...
Pedro Ganzeli
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Evolving Dimensions of Integral Education [PDF]
Integral Review, 2011 See full text PDF for details.
Judie Gaffin Wexler
doaj +2 more sources