Results 71 to 80 of about 158,353 (246)
Educação: Teoria e Prática, 2018 Integral education has been the focus of policy discussions in diverse segments within the context of Brazilian education, with special emphasis on academic productions that consider the fruitful dialogue between public policies and educational ...
Camila Arelaro Caetano
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Integrating Computation into Science Education
CBE—Life Sciences Education, 2023 This installment of Current Insights examines calls to integrate computation into science education in order to support computational thinking, practices, and literacies.
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
SENSE OF LIFE´S DEVELOPMENT IN HIGHER EDUCATION STUDENTS: A HUMANIST APPROACH
Ra Ximhai, 2018 The following work was made with the intention of contributing to the essential formation of Higher Education students. The objective of this study was to promote the development of the sense of life in the students of the Technological Institute of Los ...
Gloria Patiño-Armenta +3 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
INTEGRAL EDUCATION: SUBJECTIVE PUBLIC RIGHT
Educação: Teoria e Prática, 2018 The idea of integral education involves multiple possibilities of comprehension, particularly in policies, programs, projects, among other aspects of the organization of educational space, related to the expansion of the time that students spent in ...
Pedro Ganzeli
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Engineering Education in an Integrated Setting
International Journal of Engineering Pedagogy (iJEP), 2018 This paper serves to give brief overviews of key issues in five case studies in engineering technology stand-alone project based courses within a standard scholastic framework. The courses were offered in a range of scenarios with significant international student participation.
Richard Wood +3 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source