Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Morse oscillator equation of state: An integral equation theory based with virial expansion and compressibility terms. [PDF]
Heliyon, 2022 Al-Raeei M.
europepmc +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
A Butterfly-Accelerated Volume Integral Equation Solver for Broad Permittivity and Large-Scale Electromagnetic Analysis. [PDF]
IEEE Trans Antennas Propag, 2022 Sayed SB, Liu Y, Gomez LJ, Yucel AC.
europepmc +1 more source
Journal of Integral Equations and Applications, 2004 The author discusses the adsorption integral equation which describes the relationship between the measured adsorption isotherm and the unknown energy distribution function. Firstly he reduces the equation to the Langmuir integral equation, then shows that under rather general assumption the equation can be solved in an analytical form.
openaire +3 more sources
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Computer simulations and integral equation study of a two length scale core-softened fluid. [PDF]
J Mol Liq, 2022 Medos G, Urbic T.
europepmc +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Compression of volume-surface integral equation matrices via Tucker decomposition for magnetic resonance applications. [PDF]
IEEE Trans Antennas Propag, 2022 Giannakopoulos II +6 more
europepmc +1 more source
On the Theory of an Integral Equation
Advances in Applied Mathematics, 1994 The main object of the study in the paper is the following integral equation (1) \(x(t) = f(t) - \mu \int^ \infty_ 0 K(\tau) \text{sign} [x(t - \tau)] d \tau\). Here it is assumed that \(\mu \geq 0\), \(f\) is a continuous function having only isolated zeros \(t_ k\) such that \(f'(t_ k) \neq 0\) for \(k=1,2, \dots\). Moreover, the kernel function \(K\)
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