Results 111 to 120 of about 2,528,554 (279)

Kwong-Wong-type integral equation on time scales

Electronic Journal of Differential Equations, 2011
Consider the second-order nonlinear dynamic equation $$ [r(t)x^Delta(ho(t))]^Delta+p(t)f(x(t))=0, $$ where $p(t)$ is the backward jump operator. We obtain a Kwong-Wong-type integral equation, that is: If $x(t)$ is a nonoscillatory solution of the ...
Baoguo Jia
doaj  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Solution of nonlinear mixed integral equation via collocation method basing on orthogonal polynomials. [PDF]

Heliyon, 2022
Jan AR.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Integral equation models for solvent in macromolecular crystals. [PDF]

J Chem Phys, 2022
Gray JG, Giambaşu GM, Case DA, Luchko T.   +3 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

On the Solutions of a Quadratic Integral Equation of the Urysohn Type of Fractional Variable Order. [PDF]

Entropy (Basel), 2022
Benkerrouche A, Souid MS, Stamov G, Stamova I.   +3 more
europepmc   +1 more source

Some new nonlinear integral inequalities and their applications in the qualitative analysis of differential equations

Journal of Inequalities and Applications, 2011
In this paper, some new nonlinear integral inequalities are established, which provide a handy tool for analyzing the global existence and boundedness of solutions of differential and integral equations.
Zheng Bin, Feng Qinghua
doaj  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Volume Integral Equation Method Solution for Spheroidal Inclusion Problem. [PDF]

Materials (Basel), 2021
Lee J, Han M.
europepmc   +1 more source