Results 91 to 100 of about 4,734,779 (311)

An Algorithm for the Solution of Integro-Fractional Differential Equations with a Generalized Symmetric Singular Kernel

Fractal and Fractional
This work studies an integro-fractional differential equation (I-FrDE) with a generalized symmetric singular kernel. The scientific approach in this study was to transform the integro-differential equation (I-DE) into a mixed integral equation (MIE) with
Sameeha A. Raad, Mohammed A. Abdou
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Some properties of the functional equation ϕ(x)=f(x)+∫0λxg(x,y,ϕ(y))dy

International Journal of Mathematics and Mathematical Sciences, 1991
A discussion is given of some of the properties of the functional Volterra Integral equation ϕ(x)=f(x)+∫0λxg(x,y,ϕ(y))dy. and of the corresponding multidimensional equation.
Li. G. Chambers
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Angle-dependent integral equation theory improves results of thermodynamics and structure of rose water model. [PDF]

J Chem Phys, 2023
Ogrin P, Urbic T.
europepmc   +1 more source

On the Theory of an Integral Equation

Advances in Applied Mathematics, 1994
The main object of the study in the paper is the following integral equation (1) \(x(t) = f(t) - \mu \int^ \infty_ 0 K(\tau) \text{sign} [x(t - \tau)] d \tau\). Here it is assumed that \(\mu \geq 0\), \(f\) is a continuous function having only isolated zeros \(t_ k\) such that \(f'(t_ k) \neq 0\) for \(k=1,2, \dots\). Moreover, the kernel function \(K\)
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Hybrid Volume-Surface Integral Equation Method for Rapid Electromagnetic Simulations in MRI. [PDF]

IEEE Trans Biomed Eng, 2023
Giannakopoulos II, Guryev GD, Serralles JEC, Paska J, Zhang B, Daniel L, White JK, Collins CM, Lattanzi R.   +8 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Mixed type of Fredholm-Volterra integral equation

Le Matematiche, 2005
In this paper, under certain conditions, the solution of mixed type of Fredholm-Volterra integral equation is discussed and obtained in the space L_2 (−1, 1) × C[0, T ], T < ∞.
M. A. Abdou, G. M. Abd Al-Kader
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