Results 81 to 90 of about 150,190 (315)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
, 2012 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The boundary element method (BEM) has become a powerful method for the numerical solution of boundary-value problems (BVPs), due to its ability (at least ...
Al-Jawary, Majeed
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Canadian Journal of Mathematics, 1963 Erdélyi and Sneddon (4) have reduced the dual integral equations (4, (1.4))where Ψ is unknown, to a single Fredholm integral equation (4, (4.4)), from the solution of which Ψ is explicitly obtainable. Their work extended and clarified an investigation by Cooke (1), placing it in a context of standard integral transforms.
openaire +4 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Fredholm-Volterra integral equation with potential kernel
International Journal of Mathematics and Mathematical Sciences, 2001 A method is used to solve the Fredholm-Volterra integral equation of the first kind in the space L2(Ω)×C(0,T), Ω={(x,y):x2+y2≤a}, z=0, and ...
M. A. Abdou, A. A. El-Bary
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Perturbed conformal field theory, nonlinear integral equations and spectral problems [PDF]
, 2000 This thesis is concerned with various aspects of perturbed conformal field theory and the methods used to calculate finite-size effects of integrable quantum field theories.
Dunning, Tania Clare +2 more
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Constructive method for solvability of Fredholm equation of the first kind
Electronic Journal of Qualitative Theory of Differential Equations, 2017 The solvability and construction of the general solution of the first kind Fredholm integral equation are among the insufficiently explored problems in mathematics. There are various approaches to solve this problem.
Serikbai Aisagaliev, Zhanat Zhunussova
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The use of spline and singular functions in an integral equation method for conformal mapping
, 1980 We consider the integral equation method of Symm for the conformal mapping of simply-connected domains. For the numerical solution, we examine the use of spline functions of various degrees for the approximation of the source density o. In particular, we
Papamicheal, N, Hough, DM
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