Results 81 to 90 of about 4,734,779 (311)

Integration of Stiff Equations [PDF]

Proceedings of the National Academy of Sciences, 1952
Curtiss, C. F., Hirschfelder, J. O.
openaire   +2 more sources

Linear Integral Equations

, 1989
3
openaire   +4 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Existence of Solution to Nonlinear Third-Order Differential Equation and Iterative Method Utilization via Graph-Based Contraction

Mathematics
A new kind of graph-based contraction in a metric space is introduced in this article. We investigate results concerning the best proximity points and fixed points for these contractions, supported by illustrated examples.
Kanyuta Poochinapan, Sompop Moonchai, Tanadon Chaobankoh, Phakdi Charoensawan   +3 more
doaj   +1 more source

Existence of periodic traveling wave solutions to the generalized forced Boussinesq equation

International Journal of Mathematics and Mathematical Sciences, 1999
The generalized forced Boussinesq equation, utt−uxx+[f(u)]xx+uxxxx=h0, and its periodic traveling wave solutions are considered. Using the transform z=x−ωt, the equation is converted to a nonlinear ordinary differential equation with periodic boundary ...
Kenneth L. Jones, Yunkai Chen
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Integrability and Einstein׳s Equations

Integrable structures arise in general relativity when the spacetime possesses a pair of commuting Killing vectors admitting 2-spaces orthogonal to the group orbits. The physical interpretation of such spacetimes depends on the norm of the Killing vectors.
Korotkin, Dmitry, Samtleben, Henning
openaire   +3 more sources

Adsorption Integral Equation

Journal of Integral Equations and Applications, 2004
The author discusses the adsorption integral equation which describes the relationship between the measured adsorption isotherm and the unknown energy distribution function. Firstly he reduces the equation to the Langmuir integral equation, then shows that under rather general assumption the equation can be solved in an analytical form.
openaire   +3 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Solution of 2D non-homogenous wave equation by using polywave functions

Computer Assisted Methods in Engineering and Science, 2017
The paper presents a specific technique of solving the non-homogenous wave equation with the use of Trefftz functions for the wave equation. The solution was presented as a sum of a general integral and a particular integral.
Małgorzata Sokała
doaj