Results 71 to 80 of about 656,740 (269)
A fixed-point type result for some non-differentiable Fredholm integral equations
Mathematical Modelling and AnalysisIn this paper, we present a new fixed-point result to draw conclusions about the existence and uniqueness of the solution for a nonlinear Fredholm integral equation of the second kind with non-differentiable Nemytskii operator.
Miguel A. Hernández-Verón +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
On Carleman Integral Operators [PDF]
Proceedings of the American Mathematical Society, 1967 where Ja denotes the interval [a, b] with exception of the subintervals I x-xn I < 5; here xn denotes a finite set of points, chosen from among the points for which (3) does not hold. The question, whether a given operator can be represented in the form (1), with condition (2), was investigated by J.
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Real and Complex Techniques in Harmonic Analysis from the Point of View of Covariant Transform
, 2014 This note reviews complex and real techniques in harmonic analysis. We describe a common source of both approaches rooted in the covariant transform generated by the affine group.
Kisil, Vladimir V.
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Filomat, 2017 In this paper we construct new integral type operators including heritable properties of Baskakov Durrmeyer and Baskakov Kantorovich operators. Results concerning convergence of these operators in weighted space and the hypergeometric form of the operators are shown.
Deniz, Emre, Aral, Ali, Ulusoy, Gulsum
openaire +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Journal of Fixed Point Theory and ApplicationsAbstractWe introduce the novel concept of integral Read–Bajraktarević (iRB) operator and discuss some of its properties. We show that this iRB operator generalizes the known Read–Bajraktarević (RB) operator and we derive conditions for the fixed point of the iRB operator to belong to certain function spaces.
Jahn, Marvin, Massopust, Peter
openaire +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source