Results 101 to 110 of about 8,166 (301)
Psykhe, 2010 En un experimento de aprendizaje predictivo humano se investigó si un estímulo visual compuesto por 2 elementos es procesado como un todo (configuracionismo) o como la suma de sus elementos (elementalismo).
Gonzalo R Quintana +2 more
doaj
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Integrality of instanton numbers and p-adic B-model, Phys
, 2014 . We study integrality of instanton numbers (genus zero Gopakumar- Vafa invariants) for quintic and other Calabi-Yau manifolds. We start with the analysis of the case when the moduli space of complex structures is one-dimensional; later we show that our ...
Vadim Vologodsky +2 more
core
Aproximaciones conceptuales para diferenciar promoción de la salud de la prevención de la enfermedad
Avances en Enfermería, 1998 <p>The purpose of this paper is to establish a conceptual difference between healt promotion and illness prevention by means of reconsidering health and illness concepts.
Carda Vargas Mery Constanza
doaj
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Integrality Gaps for Sparsest Cut and Minimum Linear Arrangement Problems
, 2008 Arora, Rao and Vazirani [2] showed that the standard semi-definite programming (SDP) relaxation of the Sparsest Cut problem with the triangle inequality constraints has an integrality gap of O ( √ log n).
Nisheeth K. Vishnoi, et al.
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source