Results 91 to 100 of about 8,166 (301)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Inapproximability Reductions and Integrality Gaps

open access: yes, 2013
In this thesis we prove intractability results for several well studied problems in combinatorial optimization. Closest Vector Problem with Pre-processing (CVPP): We show that the pre-processing version of the well known CLOSEST VECTOR PROBLEM is hard to
Popat, Preyas
core  

Irreducibility, integrality and factoriality of symmetric algebras

open access: yes, 2005
Several criteria ensuring the irreducibility, integrality or factoriality of the symmetric algebra of a module over a Noetherian domain, are stated.15214760 ...
Muñoz Masqué, J., Marcelo, Agustín
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Development of communication skills in animal husbandry students of the UFPSO

open access: yesRevista Ingenio, 2017
The communicative competences constitute a fundamental tool in the training of the animal husbandry professional, from the level of its integrality and development of the occupational field. From this position, a conceptual approach was made based on the
Cesar Augusto Urón Castro
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Perception of nursing workers on the care of hypertension in older adult [PDF]

open access: yesRevista Brasileira de Enfermagem
Objective: To understand how nursing workers perceive care of hypertension (HBP) in older adult within the scope of the Family Health Strategy. Method: A qualitative descriptive study carried out in the city of Natal/RN, with 20 nursing workers ...
Rosimeire Fontes de Queiroz   +3 more
doaj   +3 more sources

On integrity

open access: yesMolecular Therapy - Nucleic Acids, 2022
Courtney Bricker-Anthony   +1 more
openaire   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Group splittings and integrality of traces

open access: yes, 2009
In this paper, we elaborate on Connes' proof of the integrality of the trace conjecture for free groups, in order to show that any action of a group G on a tree leads to a similar integrality assertion concerning the trace on the group algebra ℂ G ...
Emmanouil, I.
core  

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