Results 91 to 100 of about 8,166 (301)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Inapproximability Reductions and Integrality Gaps
In this thesis we prove intractability results for several well studied problems in combinatorial optimization. Closest Vector Problem with Pre-processing (CVPP): We show that the pre-processing version of the well known CLOSEST VECTOR PROBLEM is hard to
Popat, Preyas
core
Irreducibility, integrality and factoriality of symmetric algebras
Several criteria ensuring the irreducibility, integrality or factoriality of the symmetric algebra of a module over a Noetherian domain, are stated.15214760 ...
Muñoz Masqué, J., Marcelo, Agustín
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Development of communication skills in animal husbandry students of the UFPSO
The communicative competences constitute a fundamental tool in the training of the animal husbandry professional, from the level of its integrality and development of the occupational field. From this position, a conceptual approach was made based on the
Cesar Augusto Urón Castro
doaj +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Perception of nursing workers on the care of hypertension in older adult [PDF]
Objective: To understand how nursing workers perceive care of hypertension (HBP) in older adult within the scope of the Family Health Strategy. Method: A qualitative descriptive study carried out in the city of Natal/RN, with 20 nursing workers ...
Rosimeire Fontes de Queiroz +3 more
doaj +3 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Group splittings and integrality of traces
In this paper, we elaborate on Connes' proof of the integrality of the trace conjecture for free groups, in order to show that any action of a group G on a tree leads to a similar integrality assertion concerning the trace on the group algebra ℂ G ...
Emmanouil, I.
core

